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个人简介
Research Interests:
Dr. Lynn’s research interest is in understanding the mechanisms that regulate the formation of islet β-cells (insulin producing cells) from pancreatic stem or progenitor cells during solid organ formation in order to ameliorate and eventually cure diabetes. The Lynn laboratory focuses on the gene regulatory networks at play in the progenitor cells and how these networks change during differentiation to mature endocrine cells and in the long-term maintenance of the β-cell. A greater understanding of these genetic mechanisms and pathways will refine cell-based approaches for preventing and reversing the β-cell deterioration and loss that occurs with diabetes.
Dr. Lynn’s research interest is in understanding the mechanisms that regulate the formation of islet β-cells (insulin producing cells) from pancreatic stem or progenitor cells during solid organ formation in order to ameliorate and eventually cure diabetes. The Lynn laboratory focuses on the gene regulatory networks at play in the progenitor cells and how these networks change during differentiation to mature endocrine cells and in the long-term maintenance of the β-cell. A greater understanding of these genetic mechanisms and pathways will refine cell-based approaches for preventing and reversing the β-cell deterioration and loss that occurs with diabetes.
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论文共 119 篇作者统计合作学者相似作者
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Jelena Kolic,WenQing Grace Sun,Haoning Howard Cen,Jessica Ewald,Jason C Rogalski,Shugo Sasaki,Han Sun, Varsha Rajesh,Yi Han Xia, Renata Moravcova,Søs Skovsø,Aliya F Spigelman,
medRxiv : the preprint server for health sciences (2024)
Diabetologiano. 1 (2023): 156-169
Nobuyoshi Shimizu,Shugo Sasaki, Tomomi Taguchi,Miwa Himuro,Hirotaka Watada,FRANCIS C. LYNN,Takeshi Miyatsuka
Diabetesno. Supplement_1 (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
Naoya Shimizu,Shugo Sasaki, Tomomi Taguchi,Miwa Himuro,Hirotaka Watada,Francis C. Lynn,Takeshi Miyatsuka
DIABETES (2023)
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