基本信息
浏览量:23
职业迁徙
个人简介
Our research encompasses a range of experimental approaches, from physiological studies in humans to analysis of single cells in vitro. We use optical and electrophysiological recording techniques to monitor stimulus detection and vesicle release from endocrine cells in primary intestinal cultures, intestinal organoids and immortalized cell lines. To identify living gut endocrine cells, we have generated transgenic models in which hormone producing cells, or cellular targets of gut hormones, are labelled by cell-specific fluorescent markers and reporters of cytoplasmic signalling pathways. The mechanisms by which cells detect stimuli are identified by combining methods such as live cell imaging, electrophysiology, transcriptomics and measurements of hormone secretion using immunoassays and LC-MS.
研究兴趣
论文共 340 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Simone Mazzaferro,Hsiao-Jou Cortina Chen, Olivier Cahn,Andrian Yang, Dmytro Shepilov, Jiahui Chen, Contanza Alcaino, Viviana Macarelli,Iman Mali,Fiona Gribble,Frank Reimann,John Marioni,
biorxiv(2024)
Frontiers in endocrinology (2024): 1348146-1348146
Marito Hayashi,Judith A Kaye, Ella R Douglas,Narendra R Joshi,Fiona M Gribble,Frank Reimann, Stephen D Liberles
crossref(2023)
Laura C. Kusinski, Patrycja Tobolska, Danielle Jones, Nooria Atta,Linda M. Oude Griep,Fiona M. Gribble,CLAIRE L. MEEK
Diabetesno. Supplement_1 (2023)
引用0浏览0引用
0
0
Laura C. Kusinski,Patrycja Tobolska, Danielle Jones, Nooria Atta,Linda M. Oude Griep,Fiona M. Gribble,Claire L. Meek
DIABETES (2023)
引用0浏览0引用
0
0
Margaret Morash,Richard Kay, Jia Wen, Gilberto Padilla-Mercado, Lihua Ye,Frank Reimann,Fiona Gribble,John Rawls
引用0浏览0引用
0
0
Pei-En Chung, J. Zhang,Mariana Norton, Leah Meyer, Cecilia Dunsterville, Jieruo Liu,Fiona M. Gribble,Frank Reimann,Wenhan Chang,Kevin M. Murphy
Endocrine Abstracts (2023)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn