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The major focus of our research effort concerns the mechanisms of obesity-induced metabolic diseases such as type 2 diabetes, which is a serious disease that affects 8.3% of the population in the United States. Currently we are using molecular biology, biochemical, and cell biology approaches as well as tissue-specific transgenic and knockout mouse models to identify and characterize key molecules involved in the regulation of glucose metabolism and energy homeostasis. Particularly we are interested in how obesity leads to adipocyte dysregulation and how adipose tissue dysfunction affects whole body energy homeostasis. It is our hope that better understanding of the mechanisms underlying the crosstalk between adipose tissues and other tissues will generate important information for the development of new therapeutic drugs for the treatment of obesity-associated disorders such as Type 2 diabetes, cancer, and aging.
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BMJ supportive & palliative careno. e3 (2024): e1084-e1092
BMJ supportive & palliative careno. e3 (2024): e859-e862
Hu-Jiao Lan,Jie Ran, Wen-Xu Wang,Lei Zhang,Ni-Ni Wu, Ya-Ting Zhao, Min-Jun Huang,Min Ni,Feng Liu,Ninghui Cheng,Paul A. Nakata,Jianwei Pan,
Plant Communicationspp.100937-100937, (2024)
Guimin Zhao,Yanqi Li, Tian Chen,Feng Liu, Yi Zheng,Bingyu Liu, Wei Zhao,Xiaopeng Qi, Wanwei Sun,Chengjiang Gao
PLOS PATHOGENSno. 1 (2024): e1011902-e1011902
Jieling Zheng, Guochang Wang, Qian Ru,Yun Yang, Li Su,Wenlong Lv,Chunlin Ke,Peirong Wang,Xiaohui Liu,Li Zhang,Feng Liu,Weibing Miao
European Journal of Nuclear Medicine and Molecular Imaging (2024)
Feng Liu, Ling Tang,Huai Liu, Yanzhu Chen, Tengfei Xiao,Wangning Gu, Hongmin Yang, Hui Wang,Pan Chen
NATURE COMMUNICATIONSno. 1 (2024)
Theranosticsno. 9 (2023): 3103-3116
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BMC public healthno. 1 (2023): 1-16
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