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职业迁徙
个人简介
In 2000 and 2005 Dr. Venclovas has been awarded Howard Hughes Medical Institute international scholar grants. He was also awarded Lithuanian Science Prize (2008). Since 2016 he is a member of Lithuanian Academy of Sciences. Dr. Venclovas’ research is in the field of protein structural bioinformatics. His major scientific interests include computational analysis and prediction of three-dimensional structure of proteins and protein complexes, detection of distant evolutionary relationships between proteins, computational studies of CRISPR-Cas systems, DNA replication and repair machineries.
In Bioinformatics Laboratory we mainly deal with protein sequences and their three-dimensional structures. There are two main directions of our research:
Methods development. We aim at developing computational methods for detection of sequence homology, protein structure prediction (mainly in comparative modeling) and assessment of protein structure quality.
Application of computational methods to biological problems. Most often we use computational methods to characterize structure and interactions of both individual proteins and their complexes. In these studies we tend to focus on proteins/protein complexes that function in DNA metabolism including DNA replication, recombination and repair. Our objective is to make inferences regarding structural and functional features, molecular mechanisms, interactions, etc. that can be tested experimentally. Most of such studies are joint collaborations with experimentalists.
In Bioinformatics Laboratory we mainly deal with protein sequences and their three-dimensional structures. There are two main directions of our research:
Methods development. We aim at developing computational methods for detection of sequence homology, protein structure prediction (mainly in comparative modeling) and assessment of protein structure quality.
Application of computational methods to biological problems. Most often we use computational methods to characterize structure and interactions of both individual proteins and their complexes. In these studies we tend to focus on proteins/protein complexes that function in DNA metabolism including DNA replication, recombination and repair. Our objective is to make inferences regarding structural and functional features, molecular mechanisms, interactions, etc. that can be tested experimentally. Most of such studies are joint collaborations with experimentalists.
研究兴趣
论文共 141 篇作者统计合作学者相似作者
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Elena Manakova,Edvardas Golovinas, Reda Poceviciute,Giedrius Sasnauskas,Arunas Silanskas,Danielis Rutkauskas,Marija Jankunec,Evelina Zagorskaite, Edvinas Jurgelaitis,Algirdas Grybauskas,Ceslovas Venclovas,Mindaugas Zaremba
NUCLEIC ACIDS RESEARCHno. 5 (2024): 2530-2545
Proteomicsno. 17 (2023): e2200323-e2200323
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSno. 12 (2023): 1879-1888
Frontiers in bioinformatics (2023): 1215141
Sophia Gessner, Zela Alexandria-Mae Martin,Michael A. Reiche,Joana A. Santos,Ryan Dinkele,Atondaho Ramudzuli,Neeraj Dhar,Timothy J. de Wet,Saber Anoosheh,Dirk M. Lang,Jesse Aaron,Teng-Leong Chew,
ELIFE (2023)
Natureno. 7956 (2023): 384-389
eLife (2023)
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