Erik Hoyt - Merck & Co. | 人才画像

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Amination of a Green Solvent Via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib

Christopher K. Prier, Karla Camacho Soto,Jacob H. Forstater,Nadine Kuhl,Jeffrey T. Kuethe,Wai Ling Cheung-Lee,Michael J. Di Maso, Claire M. Eberle,Shane T. Grosser,Hsing- Ho,Erik Hoyt, Anne Maguire,Kevin M. Maloney,Amanda Makarewicz,Jonathan P. McMullen,Jeffrey C. Moore,Grant S. Murphy,Karthik Narsimhan,Weilan Pan,Nelo R. Rivera,Anumita Saha-Shah,David A. Thaisrivongs,Deeptak Verma, Adeya Wyatt,Daniel Zewge

ACS Catalysisno. 12 (2023): 7707-7714

引用2浏览0引用

Ph-Switchable Phase-Transfer Agents for Host Cell Protein Rejection in the Cascaded Biocatalytic Synthesis of an Active Pharmaceutical Ingredient

Matthew S. Winston,Marc Poirier,Zhijian Liu,Feng Peng,Guy R. Humphrey,John A. McIntosh,Mikhail Reibarkh,Fengqiang Wang,Erik D. Guetschow,Steve Castro,Erik Hoyt,David J. Lamberto,Kevin Sirk

ORGANIC PROCESS RESEARCH & DEVELOPMENTno. 1 (2023): 179-188

引用3浏览0引用

Manufacturing Process Development for the Biaryl Ether Fragment of Nemtabrutinib (MK-1026)

Nicholas R. Deprez,Harrison B. Rose,Byron K. Peters,Anthony Diaz-Santana,Zhuqing Liu,Nadine Kuhl,Cheol K. Chung, Zhu Liu,Justin A. Newman,James Corry,Erik D. Guetschow,Erik Hoyt,Lisa Jellett, Sunayana Kapil,Marc Poirier,Michael Shevlin,Eric Sirota, Andrew Solovyov,Alexandra C. Sun,David A. Thaisrivongs

ORGANIC PROCESS RESEARCH & DEVELOPMENTno. 11 (2023): 1965-1974

引用2浏览0引用

A Kinase-Cgas Cascade to Synthesize a Therapeutic STING Activator

John A. McIntosh,Zhijian Liu,Brian M. Andresen,Nastaran Salehi Marzijarani,Jeffrey C. Moore,Nicholas M. Marshall,Margie Borra-Garske,Jennifer V. Obligacion,Patrick S. Fier,Feng Peng,Jacob H. Forstater,Matthew S. Winston,Chihui An,Wonsuk Chang,Jongwon Lim, Mark A. Huffman,Steven P. Miller,Fuh-Rong Tsay,Michael D. Altman,Charles A. Lesburg,Dietrich Steinhuebel,B. Wesley Trotter,Jared N. Cumming,Alan Northrup,Xiaodong Bu,Benjamin F. Mann,Mirlinda Biba,Kaori Hiraga,Grant S. Murphy,Joshua N. Kolev,Amanda Makarewicz,Weilan Pan,Iman Farasat,Rachel S. Bade,Kevin Stone,Da Duan,Oscar Alvizo,Donovan Adpressa,Erik Guetschow,Erik Hoyt,Erik L. Regalado,Steve Castro,Nelo Rivera,Joseph P. Smith,Fengqiang Wang,Alejandro Crespo,Deeptak Verma,Stephanus Axnanda,Zachary E. X. Dance,Paul N. Devine,David Tschaen,Keith A. Canada,Paul G. Bulger,Benjamin D. Sherry,Matthew D. Truppo,Rebecca T. Ruck,Louis-Charles Campeau,David Jonathan Bennett,Guy R. Humphrey,Kevin R. Campos,Matthew L. Maddess

Nature（2022）

引用72浏览0WOSNATURE引用

Holistic Analytical Characterization and Risk Assessment of Residual Host Cell Protein Impurities in an Active Pharmaceutical Ingredient Synthesized by Biocatalysts

Fengqiang Wang,Xuanwen Li,Michael Swanson,Erik Guetschow,Matthew Winston,Joseph P. Smith,Erik Hoyt,Zhijian Liu,Douglas Richardson,Xiaodong Bu,Vibha Jawa,Narayan Variankaval

Biotechnology and Bioengineering（2022）

引用6浏览0WOS引用

Quantitation and Speciation of Residual Protein Within Active Pharmaceutical Ingredients Using Image Analysis with SDS-PAGE

Joseph P. Smith,Nicole M. Ralbovsky,Mackenzie L. Lauro,Erik Hoyt,Erik D. Guetschow,Fengqiang Wang,John A. McIntosh,Zhijian Liu,Ian Mangion,Narayan Variankaval,Xiaodong Bu

Journal of Pharmaceutical and Biomedical Analysis（2022）

引用8浏览0WOS引用

N -Glycosylamine-mediated Isotope Labeling for Mass Spectrometry-Based Quantitative Analysis of N -Linked Glycans

Bing Gong,Erik Hoyt,Heather Lynaugh,Irina Burnina,Renee Moore,Alissa Thompson,Huijuan Li

Analytical and Bioanalytical Chemistry（2013）

引用27浏览0WOS引用

A Cost-Effective Plate-Based Sample Preparation for Antibody N-glycan Analysis

Irina Burnina,Erik Hoyt,Heather Lynaugh,Huijuan Li,Bing Gong

Journal of Chromatography A（2013）

引用31浏览0WOS引用

High-throughput Multimodal Strong Anion Exchange Purification and N-glycan Characterization of Endogenous Glycoprotein Expressed in Glycoengineered Pichia Pastoris

Sujatha Gomathinayagam,Erik Hoyt, Alissa M Thompson,Eric Brown,Khanita Karaveg,Stephen R Hamilton,Huijuan Li

Methods in molecular biology (Clifton, NJ)（2012）

引用1浏览0WOS引用

Elimination of -Mannose Glycan Structures in Pichia Pastoris

Daniel Hopkins,Sujatha Gomathinayagam,Alissa M. Rittenhour,Min Du,Erik Hoyt,Khanita Karaveg,Teresa Mitchell,Juergen H. Nett,Nathan J. Sharkey,Terrance A. Stadheim,Huijuan Li,Stephen R. Hamilton

Glycobiology（2011）

引用35浏览0WOS引用

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