基本信息
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职业迁徙
个人简介
Area(s) of interest
Etiology of respiratory and gastrointestinal infections
Clinical relevance of molecular diagnostics
Innovation in the molecular diagnostic workflow
The role of NGS in diagnostic microbiology
Research interests
The Molecular Diagnostics lab of the clinical microbiology lab is specialized in implementation of molecular assays for diagnosis of infections in the whole field of microbiology, and by now more than 100 real-time PCR assays have been implemented in the diagnostic lab. Using multiplex applications up to five different targets, the focus can be more syndrome related than pathogen related. For respiratory infections and gastroenteritis, viruses, bacteria and parasites are tested simultaneously to rapidly identify the cause.
Currently, laboratory automation and further improvements in laboratory efficiency and service are high on the agenda. Recently rapid syndromic test panels have been implemented to increase the time to results for respiratory testing.
Furthermore the possibilities of Next Generation sequencing in Molecular Diagnostic practice are being explored. For bacterial typing in infection control, cgMLST and wgSNP analysis have been developed for some of the major outbreak related micro-organisms.
In addition, protocols metagenomic WGS in detection of pathogens are being optimized.
研究兴趣
论文共 114 篇作者统计合作学者相似作者
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Medical mycology (2024)
Stefan A. Boers, Robin van Houdt, Nina M. van Sorge, Jelle Groot, Yvette van Aarle,Mario J. A. W. M. van Bussel, Louise F. E. Smit,Els Wessels,Eric C. J. Claas
medRxiv (Cold Spring Harbor Laboratory) (2023)
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Miae Lee,Eliseo Albert,Els Wessels,Soo-Kyung Kim,Hae-Sun Chung,Estela Giménez, Tom Vreeswijk,Eric C J Claas, Yan Chin Tai,Birgit Reinhardt,Mark M Sasaki,David Navarro
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Emerging infectious diseasesno. 5 (2023): 1055-1057
Maria M Konstantinovski,Leo M Schouls,Sandra Witteveen,Eric C J Claas,Margriet E Kraakman, Jayant Kalpoe, Eva Mattson,David J Hetem, Erika P M van Elzakker,Jos Kerremans, Vishal Hira,Thijs Bosch,
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