Edward H. Koo

University of California, San Diego, La Jolla, CA, USA.

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Papers162 papers

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The chemo-brain effect in colorectal cancer patients

Matilda Lee, Wan Qin Chong, Hon Lyn Tan, Gloria Chan,Jingshan Ho,Raghav Sundar, Cheng Ean Chee, Fatima Nasrallah,Edward H Koo,Wei-Peng Yong

Journal of Clinical Oncology, (2020)

Bibtex

Aβ-induced synaptic injury is mediated by presynaptic expression of amyloid precursor protein (APP) in hippocampal neurons

Elena Vicario-Orri, Kensaku Kasuga,Sheue-Houy Tyan, Karen Chiang, Silvia Viana da Silva,Eric A. Bushong,Katherine DeLoach, I-Fang Ling,Liqun Luo,Mark H. Ellisman, Stefan Leutgeb,Edward H. Koo

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Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer's Disease

Goonho Park, Hoang S Nhan,Sheue-Houy Tyan, Yusuke Kawakatsu, Carolyn Zhang, Mario Navarro,Edward H Koo

Cell Reports, no. 13 (2020): 107839

WOSBibtex

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke

Luting Poh, Sung-Wook Kang,Sang-Ha Baik, Gavin Yong Quan Ng, David T She, Priyanka Balaganapathy,S Thameem Dheen,Tim Magnus,Mathias Gelderblom,Christopher G Sobey,Edward H Koo, David Y Fann

Elements, (2020)

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FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits

Wan Yun Ho, Jer-Cherng Chang,Sheue-Houy Tyan, Yi-Chun Yen, Kenneth Lim, Bernice Siu Yan Tan, Jolynn Ong,Greg Tucker-Kellogg, Peiyan Wong,Edward Koo, Shuo-Chien Ling

Human molecular genetics, (2019)

WOSBibtex

Cerebral transcriptome analysis reveals age-dependent progression of neuroinflammation in P301S mutant tau transgenic male mice

Joonki Kim, Sharmelee Selvaraji, Sung Wook Kang, Wei Thye Lee,Christopher Li-Hsian Chen,Hyungwon Choi,Edward H Koo,Dong-Gyu Jo,Kah Leong Lim, Yun-An Lim,Thiruma V Arumugam

Brain, Behavior, and Immunity, (2019): 344-357

WOSBibtex

PERK-mediated induction of microRNA-483 disrupts cellular ATP homeostasis during the unfolded protein response

Nobuhiko Hiramatsu, Karen Chiang, Cathrine Aivati,Jeffrey J Rodvold, Ji-Min Lee, Jaeseok Han, Leon Chea,Maurizio Zanetti,Edward H Koo,Jonathan H Lin

The Journal of biological chemistry, no. 1 (2019): 237-249

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Microinterventional endocapsular nucleus disassembly for phacoemulsification-free full-thickness fragmentation

Tsontcho Ianchulev, David F Chang,Edward Koo, Susan MacDonald

Journal of Cataract & Refractive Surgery, no. 8 (2018): 932-934

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Evidence that NLRC4 Inflammasome Mediates Apoptotic and Pyroptotic Microglial Death Following Ischemic Stroke

Luting Poh, Sung-Wook Kang,Sang-Ha Baik, Gavin Yong Quan Ng, David T She, Priyanka Balaganapathy,S Thameem Dheen,Tim Magnus,Mathias Gelderblom,Christopher G Sobey,Edward H Koo, David Y Fann

Brain, Behavior, and Immunity, (2018): 34-47

Cited by1WOSBibtex

Tauopathy-Associated PERK Alleles are Functional Hypomorphs that Increase Neuronal Vulnerability to ER Stress

Shauna H Yuan,Nobuhiko Hiramatsu,Qing Liu, Xuehan Victoria Sun, David Lenh,Priscilla Chan,Karen Chiang,Edward H Koo, Aimee W Kao,Irene Litvan,Jonathan H Lin

Human molecular genetics, (2018)

Cited by4WOSBibtex

Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before

Liying Corinne Lee, Michele Q. L. Goh,Edward H. Koo,Edward H. Koo

BioEssays, no. 9 (2017): 1700062

Cited by2Bibtex

APLP1 is a synaptic cell adhesion molecule, supporting maintenance of dendritic spines and basal synaptic transmission

Sandra Schilling, Annika Mehr, Susann Ludewig,Jonathan Stephan, Marius Zimmermann, Alexander August, Paul Strecker,Martin Korte,Edward H. Koo,Ulrike Müller,Stefan Kins,Simone Eggert

The Journal of neuroscience : the official journal of the Society for Neuroscience, no. 21 (2017): 5345-5365

Cited by9WOSBibtex

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

Simone Eggert, A C Gonzalez, C Thomas,S Schilling, S M Schwarz,C Tischer, V Adam, P Strecker,V Schmidt,T E Willnow,G Hermey,C U Pietrzik

Cellular and molecular life sciences : CMLS, no. 2 (2017)

Cited by4WOSBibtex

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Chao Liu,Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong,Liying Corinne Lee,Wei Yi Ong, Sung Ok Yoon,Wanjin Hong, Xin-Yuan Fu,Tuck Wah Soong,Edward H Koo,Lawrence W Stanton

Cell death and differentiation, (2017)

Cited by2WOSBibtex

SINGAPORE INTERVENTION STUDY TO PREVENT COGNITIVE IMPAIRMENT AND DISABILITY (SINGER) INITIATIVE

Christopher Chen,Xin Xu, Effie Chew, Christiani Jeyakumar Henry,Edward H. Koo

Alzheimers & Dementia, no. 7 (2017): 1222

Cited by2Bibtex

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology

Jeffrey N Savas, Yi-Zhi Wang,Laura A DeNardo,Salvador Martinez-Bartolome,Daniel B McClatchy, Timothy J Hark,Natalie F Shanks, Kira A Cozzolino,Mathieu Lavallée-Adam, Samuel N Smukowski,Sung Kyu Park,Jeffery W Kelly

Cell Reports, no. 9 (2017): 2614-2627

Cited by8WOSBibtex

Short Aβ peptides attenuate Aβ42 toxicity in vivo

Brenda D Moore,Jason Martin, Lorena de Mena,Jonatan Sanchez,Pedro E Cruz,Carolina Ceballos-Diaz,Thomas B Ladd,Yong Ran,Yona Levites,Thomas L Kukar, Justin J Kurian,Robert McKenna

The Journal of experimental medicine, (2017)

Cited by5WOSBibtex

The Utility of Brief Cognitive Tests for Patients With Type 2 Diabetes Mellitus: A Systematic Review

YanHong Dong,YanHong Dong, Zhong Jie Kua,Eric Yin Hao Khoo,Edward H. Koo,Reshma A. Merchant

Journal of the American Medical Directors Association, no. 10 (2016): 889-895

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Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice

Sun Ah Park,Nathalie Chevallier, Karishma Tejwani, Mary M. Hung,Hiroko Maruyama,Todd E. Golde,Edward H. Koo

Biochemical and Biophysical Research Communications, no. 1 (2016): 286-292

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Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator

Joo In Jung,Ashleigh R Price,Thomas B Ladd,Yong Ran,Hyojin Park,Carolina Ceballosdiaz,Lisa A Smithson,Gunther Hochhaus,Yufei Tang, Rajender Akula, Saritha Ba,Edward H Koo

Molecular Neurodegeneration, no. 1 (2015): 29

Cited by4Bibtex

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