Edward A Fitzgerald - Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA

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Bio

Marie Skłodowska-Curie Industry Fellow as part of the FragNet consortium at Uppsala University and Beactica Therapeutics. Keen interest in biophysical methods for drug discovery. Research interests include, microfluidics, protein therapies, drug design, tissue engineering, in-vitro organ models, molecular modeling and protein engineering.

Research Interests

Papers共 24 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-Step Array Synthesis with HT Crystallography

Harold Grosjean,Anthony Aimon,Storm Hassell-Hart,Warren Thompson,Lizbé Koekemoer,James Bennett,Anthony Bradley, Cameron Anderson,Conor Wild, William J Bradshaw,Edward A FitzGerald,Tobias Krojer,Oleg Fedorov,Philip C Biggin,John Spencer,Frank von Delft

Angewandte Chemie (International ed in English)（2025）

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Integrated Computational and Biosensor-Based Strategies for the Discovery of Allosteric SMYD3 Ligands Using Diperodon As a Starting Point

Edward A FitzGerald, Moira M Rachman,Daniela Cederfelt, Nadine E M Myers, Daria Kovryzchenko, He Zhang,Xavier Barril, Konrad Koehler,U Helena Danielson

Bioorganic & medicinal chemistry (2025): 118134-118134

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Efficient Large-Scale Exploration of Fragment Hit Progression by Exploiting Binding-Site Purification of Actives (B-SPA) Through Combining Multi-Step Array Synthesis and HT Crystallography

Harold Grosjean,Anthony Aimon,Storm Hassell-Hart,Warren Thompson,Lizbé Koekemoer, James Bennett, Cameron Anderson,Conor Wild,William Bradshaw,Edward A FitzGerald, Tobias Krojer,Anthony Bradley,Oleg Fedorov, Philip C. Biggin,John Spencer,Frank von Delft

openalex（2024）

Cited1Views0Bibtex

Identification of Fragments Targeting SMYD3 Using Highly Sensitive Kinetic and Multiplexed Biosensor-Based Screening

Edward A. FitzGerald,Daniela Cederfelt,Bjarte Aarmo Lund, Nadine E. M. Myers, He Zhang,Doreen Dobritzsch,U. Helena Danielson

RSC MEDICINAL CHEMISTRYno. 6 (2024): 1982-1990

Cited1Views0WOSBibtex

Accelerating BRPF1b Hit Identification with BioPhysical and Active Learning Screening (Biopals)

Sandeep Pal, Zandile Nare,Vincenzo A. Rao,Brian O. Smith, Ian Morrison,Edward A. Fitzgerald,Andrew Scott,Matilda J. Bingham,Thomas Pesnot

CHEMMEDCHEMno. 6 (2024)

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Multiplexed Experimental Strategies for Fragment Library Screening Against Challenging Drug Targets Using SPR Biosensors

Edward A. FitzGerald,Darius Vagrys,Giulia Opassi,Hanna F. Klein,David J. Hamilton,Vladimir O. Talibov,Mia Abramsson,Anna Moberg,Maria T. Lindgren, Claes Holmgren,Ben Davis,Peter O. ' Brien,Maikel Wijtmans,Roderick E. Hubbard, Iwan J. P. de Esch,U. Helena Danielson

SLAS DISCOVERY（2023）

Cited4Views0WOSBibtex

High-throughput Crystallography for Rapid Early-Stage Fragment Growth from Crude Arrays by Low-Cost Robotics

Harold Grosjean, A. Aimon,Storm Hassell-Hart,Warren A. Thompson, L. Koekemoer,James M. Bennett, Cameron Anderson,Edward A. Fitzgerald, T. Krojer, A.R. Bradley,O. Fedorov,Philip C. Biggin,John Spencer,Frank von Delft

Zenodo (CERN European Organization for Nuclear Research) (2023)

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High-throughput crystallography for rapid fragment growth from crude arrays by low-cost robotics

Harold Grosjean,Anthony Aimon,Storm Hassell-Hart,Warren Thompson,Lizbé Koekemoer,James Bennett, Cameron Anderson,Edward A FitzGerald,Tobias Krojer,Anthony Bradley,Oleg Fedorov,Philip C. Biggin,John Spencer,Frank von Delft

crossref（2023）

Cited1Views0Bibtex

Discovery of Fragments Inducing Conformational Effects in Dynamic Proteins Using a Second-Harmonic Generation Biosensor

Edward A. FitzGerald,Margaret T. Butko,Pierre Boronat,Daniela Cederfelt,Mia Abramsson, Hildur Ludviksdottir,Jacqueline E. Van Muijlwijk-Koezen,Iwan J. P. de Esch,Doreen Dobritzsch,Tracy Young,U. Helena Danielson

RSC Advances（2021）

Cited7Views0WOSBibtex

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