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Throughout his distinguished academic career, Dr. Albuquerque studied the effects of different toxicants, including lead and organophosphorus compounds, nerve agents and insecticides, on neuronal functions in vitro and in vivo. He researched nicotinic and glutamatergic synapses in the central nervous system, which are known to be involved in cognition, learning, and memory, as well as several pathological conditions, such as Alzheimer's disease and epilepsy.
Dr. Albuquerque’s research laid the groundwork for the development of a new class of drugs for the treatment of Alzheimer's disease - the so-called "nicotinic allosteric potentiating ligands, of which galantamine is the prototype. Research in his laboratory has aided in the development of treatments for neuropathological conditions that afflict millions of people worldwide.
Dr. Albuquerque had received international recognition for his electrophysiological research on neurotransmitter receptors in the central and peripheral nervous systems, including the Order of the Grand Cross and the Rio Branco Award from Brazil, and in the United States, from the NIH the prestigious Jacob Javits Award Neuroscience Research Award and the Otto Krayer Award from the American Society for Pharmacology and Experimental Therapeutics.
Dr. Albuquerque’s research laid the groundwork for the development of a new class of drugs for the treatment of Alzheimer's disease - the so-called "nicotinic allosteric potentiating ligands, of which galantamine is the prototype. Research in his laboratory has aided in the development of treatments for neuropathological conditions that afflict millions of people worldwide.
Dr. Albuquerque had received international recognition for his electrophysiological research on neurotransmitter receptors in the central and peripheral nervous systems, including the Order of the Grand Cross and the Rio Branco Award from Brazil, and in the United States, from the NIH the prestigious Jacob Javits Award Neuroscience Research Award and the Otto Krayer Award from the American Society for Pharmacology and Experimental Therapeutics.
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