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Our research focus is centered on elucidating the role that transcriptional and epigenetic regulators play in normal and cancer development, and therapeutic response. We are passionate about asking clinically relevant questions and translating basic laboratory findings into therapeutic applications to benefit cancer patients while at the same time providing new insights into the fundamental mechanisms of how epigenetic regulators regulate transcription and dictate cell identity. To achieve these goals, the Toska lab aims to undertake a multidisciplinary approach integrating biochemistry, cell signaling, genomics, and epigenomics at bulk and single-cell level, organoid technology, and mouse genetics to study the fundamental processes by which epigenetic regulators regulate transcription, cross-talk with signaling pathways, and have the ability to drive transformation and dictate therapeutic response in nuclear receptor-dependent cancers. Our laboratory will be comprised of scientists from different fields who are driven to study epigenetic regulation in normal and cancer development and to identify new therapeutic opportunities.
Our research focus is centered on elucidating the role that transcriptional and epigenetic regulators play in normal and cancer development, and therapeutic response. We are passionate about asking clinically relevant questions and translating basic laboratory findings into therapeutic applications to benefit cancer patients while at the same time providing new insights into the fundamental mechanisms of how epigenetic regulators regulate transcription and dictate cell identity. To achieve these goals, the Toska lab aims to undertake a multidisciplinary approach integrating biochemistry, cell signaling, genomics, and epigenomics at bulk and single-cell level, organoid technology, and mouse genetics to study the fundamental processes by which epigenetic regulators regulate transcription, cross-talk with signaling pathways, and have the ability to drive transformation and dictate therapeutic response in nuclear receptor-dependent cancers. Our laboratory will be comprised of scientists from different fields who are driven to study epigenetic regulation in normal and cancer development and to identify new therapeutic opportunities.
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论文共 71 篇作者统计合作学者相似作者
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Higinio Dopeso, Yingjie Zhu, Laxmi Gusain, Thais Basili, David Brown, Fatemeh Derakhshan, Edaise M. da Silva, Richard Koche, Pierre-Jacques Hamard,Xinyu Guo,Eneda Toska, Elisa DeStanchina,
Cancer Researchno. 6_Supplement (2024): 3936-3936
Nadeem Bilani,Jacqueline Tao, Anton Safonov,Dana Casey, Joshua Drago, Mehnaj Ahmed,Barbara Acevedo, Komal Jhaveri,Jorge Reis-Filho, Mark Robson,Eneda Toska,Ariella Hanker,
Cancer Researchno. 9_Supplement (2024): PO5-15
Biochimica et Biophysica Acta (BBA) - Reviews on Cancerno. 3 (2024): 189097-189097
Kasturee Jagirdar,Marie E. Portuallo,Meihan Wei, Matthew Wilhide,Jeremy A. Bravo Narula, Bailey M. Robertson,Gretchen M. Alicea, Crystal Aguh,Min Xiao,Tetiana Godok,Dylan Fingerman,Gregory Schuyler Brown,
Research squareno. 6 (2024): 395-405
CANCER DISCOVERYno. 6 (2023): 1428-1453
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Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap,William Jacot,Robert H. Jones,Huiyan Eng,Madhumathy G. Nair,Pooyan Makvandi,Birgit Geoerger,Matthew H. Kulke,Richard D. Baird,
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