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Dr. Mezey is interested in the biology of bone marrow stromal cells (MSCs). These cells are able to suppress the immune system and have been tested in autoimmune diseases. The same cells also support hematopoiesis (making of blood cells) in the bone marrow. Her studies suggest that injected MSCs might be able to alleviate sepsis in patients. Studies also reveal that—through a different mechanism—these cells might reduce the symptoms of asthma. Her group studies ways in which to improve the efficiency of these cells in fighting auto-immune diseases. In addition, they are studying how MSCs might regulate red cell production in the bone marrow of patients with anemia. Dr. Mezey’s group collaborates with clinicians to find out the best ways to use the unique properties of these cells in patients, and to prime MSCs for targeted use.
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Miklós Krepuska,Balázs Mayer,Lynn Vitale-Cross, Vamsee D. Myneni,Michael K. Boyajian,Krisztián Németh,Ildikó Szalayova, Ted Cho, Ian Mc Clain-Caldwell,Aaron D. Gingerich,Huiling Han,Mark Westerman,
Scientific Reportsno. 1 (2024): 1-13
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bioRxiv (Cold Spring Harbor Laboratory) (2021)
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