For more than 20 years, he has been involved in clinical research for breast cancer and cancer in older patients. He chaired the group GERICO (Unicancer) and the intergroup DIALOG labeled by INCa dedicated to clinical research for cancer in older persons. He chaired the breast cancer group of EORTC and is the EORTC Secretary General since 2021. He is an executive board member of the Breast International Group and past-president of the International Society of Geriatric Oncology.

He received the B.J. Kennedy Award for Scientific Excellence in Geriatric Oncology (ASCO 2022), the Michel Hery geriatric oncology Award (Monaco Age Oncologie conference 2023) and the Prix Albert 1er of the Académie Nationale de Médecine (Biennale Monégasque de Cancérologie 2024).