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Dorret I. Boomsma (born 18 November 1957, Huizen, The Netherlands) is a Dutch biological psychologist specializing in genetics and twin studies.
After receiving her Ph.D., Boomsma received an appointment as an assistant professor at the Vrije Universiteit in the Department of Psychonomics. In 1994 she became associate and in 1998 full professor and head of the Department of Biological Psychology。
Boomsma has built a database of over 75,000 twins and family members in The Netherlands, which has been used for dozens of twin studies. The twins and their families have undergone periodic testing over a period of decades, providing a mass of longitudinal data for statistical analysis. A large number of participants have also provided DNA, blood, and urine samples for testing. Her research has primarily focused on better understanding the influence of heredity on various physical and mental diseases, including cardiovascular diseases, pediatric bipolar disorder, and depression. This work has been reported in over 450 published papers and one book and has led to many awards for Boomsma.
Twin studies provide a way to understand how genotype affects an observable characteristic (called a phenotype). In short, identical (monozygotic) twins carry the same alleles for 100% of their genes whereas fraternal (dizygotic) twins will carry different alleles at 50% of the genes for which their parents had different genotypes. So if some characteristic (say, depression) that is observed in one identical twin is always observed in the other one, but this does not hold for fraternal twins, then one can conclude that heredity plays an important role in causing the condition.
Boomsma has been a pioneer in collecting a broad spectrum of data (e.g., medical histories, IQ tests, MRI scans) and biological material (e.g., DNA and RNA samples, blood and urine samples) from thousands of twins and analyzing them to determine the role of genetics in characteristics as varied as adult height, brain volume, intelligence, migraine headaches, anxiety, drug addiction, and love of coffee.
Her results span a wide range of behavioral characteristics, including discovery of the surprisingly large genetic component to feelings of loneliness, the fact that first borns have higher IQs than their younger siblings, and the increased influence of genetics on body weight as children grow older.
研究兴趣
论文共 314 篇作者统计合作学者相似作者
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Bodine M.A. Gonggrijp, Steve G.A. van de Weijer, Catrien C.J.H. Bijleveld,Dorret I Boomsma,Jenny van Dongen
biorxiv(2024)
Fiona A. Hagenbeek, René Pool, Austin J. Van Asselt,Erik A. Ehli, Meike Bartels,Jouke Jan Hottenga, Conor V. Dolan, Jenny van Dongen,Dorret I. Boomsma
medrxiv(2024)
Nikki Hubers,Fiona A. A. Hagenbeek,Rene Pool,Sebastien Dejean,Amy C. C. Harms, Peter J. J. Roetman, Catharina E. M. van Beijsterveldt,Vassilios Fanos,Erik A. A. Ehli, Robert R. J. M. Vermeiren,Meike Bartels,Jouke Jan Hottenga,
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICSno. 2 (2024)
Ruiyang Ge,Yuetong Yu, Yi Xuan Qi, Yu-nan Fan, Shiyu Chen, Chuntong Gao,Shalaila S Haas,Faye New,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Randy Buckner,
The Lancet Digital Healthno. 3 (2024): e211-e221
HUMAN REPRODUCTIONno. 1 (2024): 35-42
Guanglu Li,Guanglu Li,Shaojie Duan, International Headache Genetics Consortium (IHGC), Tao Zheng, Tiantian Zhu, Baoquan Qu,Lei Liu,Zunjing Liu,Verneri Anttila,Ville Artto, Andrea C Belin,
Frontiers in Immunology (2024)
GENESno. 7 (2023): 1497-1497
S. Zwaveling,S. Bloemen,E. Castoldi, E. Geus, de, J. Hottenga,T. Hackeng,D. Boomsma,G. Willemsen, C. Hemker
Research and Practice in Thrombosis and Haemostasis (2023): 100667-100667
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