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个人简介
I began my research as a junior doctor when I became interested in why a patient developed muscle pain on exercise. This led me to start my studies on mitochondria and disease which have continued to fascinate me to this day. My PhD studies focused on understanding the molecular mechanisms in mitochondrial disease “Mitochondrial Cytopathies: Clinical and Experimental Studies”. At the same time I completed an MD which focused on the anticonvulsant drug sodium valproate but I was particularly interested in the toxicity of sodium valproate which involves mitochondria “Sodium Valproate: Clinical and Biochemical Studies”.
On completion of my research degrees I became a Lecturer in Experimental Neurology and continued my research into mitochondrial disease. In 1990 I became Professor of Neurology at Newcastle University and this allowed me to develop my clinical and molecular studies of mitochondrial disease. One of the great strengths of working in the UK is the ability to link clinical studies to basic research and this highlight my main research interest and expertise. Building upon research which started over two decades ago we have been able to build the Wellcome Trust Centre for Mitochondrial Research along with a world class clinical service for patients.
研究兴趣
论文共 258 篇作者统计合作学者相似作者
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Mitochondrion (2018): 302-306
Ewen W. Sommerville,Yi Shiau Ng,Charlotte L. Alston,Cristina Dallabona,Micol Gilberti,Langping He,Charlotte Knowles, Sophie L. Chin,Andrew M. Schaefer,Gavin Falkous, David Murdoch,Cheryl Longman,
Journal of Cachexia, Sarcopenia and Muscle - Clinical Reportsno. 2 (2017): 1-10
Neurology. Geneticsno. 6 (2017): e202-e202
Ahmad A. Khundakar,Peter S. Hanson,Daniel Erskine,Nichola Z. Lax, Joseph Roscamp,Evangelia Karyka, Eliona Tsefou,Preeti Singh,Simon J. Cockell, Andrew Gribben,Lynne Ramsay,Peter G. Blain,
Natureno. 7607 (2016): 383-386
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