基本信息
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职业迁徙
个人简介
Dirk does research in Cell Biology, Molecular Biology and Cancer Research.
Research:
In close collaboration with clinicians we're investigating aberrantly activated signaling cues in cancer with the final goal to find new concepts for therapeutic intervention in malignant diseases.
To this aim we're applying state-of-the-art cell biological and biochemical methods and analyse potential drug targets in murine tumor models.
Spatial intracellular signalling of oncogenic cytokine receptors.
We currently analyse if aberrant localisation of active cytokine receptors is responsible for downstream signal quality und subsequent oncogenic processes.
The role of ADAM-proteases in liver pathologies.
The impact of ADAM-proteases and its regulators on the metastatic process.
Research:
In close collaboration with clinicians we're investigating aberrantly activated signaling cues in cancer with the final goal to find new concepts for therapeutic intervention in malignant diseases.
To this aim we're applying state-of-the-art cell biological and biochemical methods and analyse potential drug targets in murine tumor models.
Spatial intracellular signalling of oncogenic cytokine receptors.
We currently analyse if aberrant localisation of active cytokine receptors is responsible for downstream signal quality und subsequent oncogenic processes.
The role of ADAM-proteases in liver pathologies.
The impact of ADAM-proteases and its regulators on the metastatic process.
研究兴趣
论文共 57 篇作者统计合作学者相似作者
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Journal of clinical immunologyno. 1 (2023): 30-30
Biochimica et Biophysica Acta (BBA) - Molecular Cell Researchno. 7 (2023): 119489-119489
Lisa Charlotte Heinig, Emily Valentina Madelaine Huth,Karsten Yan,Neele Schumacher,Mikolaj Nawrocki,Niels Christian Lory,Peter Bradtke,Tabea Bertram,Guido Rattay,Joanna Schmid,Samuel Huber,Thorsten Wiech,
Miryam Müller, Claire Saunders, Anke Senftleben, Johannes P W Heidbuechel, Birgit Halwachs,Julia Bolik,Nina Hedemann,Christian Röder,Dirk Bauerschlag,Stefan Rose-John,Dirk Schmidt-Arras
Julia Bolik, Freia Krause, Marija Stevanovic, Monja Gandraß,Ilka Thomsen,Sarah-Sophie Schacht,Eva Rieser,Miryam Müller,Neele Schumacher,Jürgen Fritsch,Rielana Wichert,Eithan Galun,
Jürgen Fritsch, Julia Frankenheim, Lothar Marischen,Timea Vadasz,Anja Troeger,Stefan Rose-John,Dirk Schmidt-Arras,Wulf Schneider-Brachert
The Journal of allergy and clinical immunologyno. 2 (2021): 585-598
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