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个人简介
Dr. Wu’s lab is interested in the mechanisms and functions of chemoattractant and Wnt-activated signaling. Chemoattractants, including chemokines, play an important role in host defense. However, their unchecked activities contribute to may inflammation-related diseases, including atherosclerosis, arthritis, tumorigenesis, and various allergies. The Wnt family of secretory glycoproteins participates in a wide variety of developmental events including, control of cell growth, generation of cell polarity, and specification of cell fate. Wnt pathways have been also closely linked to tumorigenesis, glucose metabolism, and bone formation. We are using a combination of molecular and cell biological, biochemical, chemical biological, transgenic, functional genomic, and proteomic approaches to discover novel signaling mechanisms and functions for these signaling proteins.
研究兴趣
论文共 27 篇作者统计合作学者相似作者
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Yi Luan,Jiajia Hu, Qijun Wang, Xujun Wang,Wenxue Li, Rihao Qu, Chuan Yang, Barani Kumar Rajendran,Hongyue Zhou, Peng Liu, Ningning Zhang, Yu Shi,
Cell Reportsno. 3 (2024): 113934-113934
Jichang Han, Meng Yu, Yiqin Bai,Jianzhong Yu,Fei Jin,Chen Li,Rong Zeng, Jinghong Peng,Ao Li,Xiaomin Song,Hao Li,Dianqing Wu,
Jinxia Sun,Yi Luan, Dong Xiang,Xiao Tan,Hui Chen,Qi Deng,Jiaojiao Zhang,Minghui Chen,Hongjun Huang,Weichao Wang, Tingting Niu, Wenjie Li,
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