McGinnity Dermot F - Department of Physical &Metabolic Science, AstraZeneca R&D Charnwood

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论文共 57 篇作者统计合作学者相似作者

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Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier

Nicola Colclough,Ravindra V Alluri,James W Tucker,Elnaz Gozalpour,Danxi Li, Hongwen Du, Wei Li,Stephanie Harlfinger, Daniel J O'Neill,Graham G Sproat,Kan Chen, Yumei Yan,

Drug metabolism and disposition: the biological fate of chemicalsno. 2 (2024): 95-105

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Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain BarrierS

Nicola Colclough,Ravindra V. Alluri, James W. Tucker, Elnaz Gozalpour,Danxi Li, Hongwen Du, Wei Li, Stephanie Harlfinger, Daniel J. O'Neill,Graham G. Sproat,Kan Chen, Yumei Yan,

DRUG METABOLISM AND DISPOSITIONno. 2 (2024): 95-105

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Pharmacokinetic evaluation of poorly soluble compounds formulated as nano- or microcrystals after intraperitoneal injection to mice

Krishna C Aluri,Kalle Sigfridsson,Aixiang Xue,Niresh Hariparsad,Dermot McGinnity,Diane Ramsden

Int J Pharm（2023）

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The Disconnect in Intrinsic Clearance Determined in Human Hepatocytes and Liver Microsomes Results from Divergent Cytochrome P450 Activities

Tashinga E. Bapiro,Scott Martin, Stephen D. Wilkinson, Alexandra L. Orton,Niresh Hariparsad, Stephanie Harlfinger,Dermot F. McGinnity

DRUG METABOLISM AND DISPOSITIONno. 7 (2023): 892-901

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Interspecies evaluation of a physiologically based pharmacokinetic model to predict the biodistribution dynamics of dendritic nanoparticles

Christina Vasalou,Joanna Harding,Rhys D O Jones,Niresh Hariparsad,Dermot F McGinnity

PLoS ONEno. 5 (2023): e0285798-e0285798

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A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models

Michael J. White, Letitia Cheatham,Shenghua Wen, Graeme Scarfe,Justin Cidado,Corinne Reimer,Niresh Hariparsad,Rhys D. O. Jones,Lisa Drew,Dermot F. McGinnity,Christina Vasalou

The AAPS journalno. 4 (2023): 66-8

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Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes

Christina Vasalou,Douglas Ferguson, Weimin Li,Victorine Muse,Francis D Gibbons,Silvia Sonzini,Guangnong Zhang,Petar Pop-Damkov,Eric Gangl,Srividya B Balachander,Shenghua Wen,Alwin G Schuller,

MOLECULAR PHARMACEUTICS（2022）

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Challenges and Opportunities for Improved Drug‐Drug Interaction Predictions for Renal OCT2 and MATE1 / 2‐K Transporters

Srinivasan Krishnan,Diane Ramsden,Douglas Ferguson,Simone H. Stahl,Joanne Wang,Dermot F. McGinnity,Niresh Hariparsad

Clinical Pharmacology & Therapeutics (2022)

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Challenges and Opportunities for Improved Drug-Drug Interaction Predictions for Renal OCT2 and MATE1/2-K Transporters

Srinivasan Krishnan,Diane Ramsden,Douglas Ferguson,Simone H Stahl,Joanne Wang,Dermot F McGinnity,Niresh Hariparsad

CLINICAL PHARMACOLOGY & THERAPEUTICSno. 3 (2022): 562-572

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ADME and DMPK considerations for the Discovery and Development of Antibody Drug Conjugates (ADCs)

Kevin Beaumont,Andy Pike,Michael Davies, Adriana Savoca,Christina Vasalou, Steffi Harlfinger,Diane Ramsden,Douglas Ferguson,Niresh Hariparsad, Owen Jones,Dermot McGinnity

Xenobiotica（2022）

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