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My long-term goal is to understand how the hypothalamus is able to achieve its diverse, but highly integrated control of basic physiological processes. All of the research projects initiated in my laboratory, or through collaborations with other research labs at the University of Toronto or globally, will help to define the molecular mechanisms involved in the neuroendocrine events initiated at the level of the hypothalamus through the analysis of specific cell models.
The main focus of my laboratory is to understand, at the molecular level, how the hypothalamus achieves its diverse physiological functions. The neuroendocrine hypothalamus consists of a complex array of distinct neuronal phenotypes, each expressing a specific complement of neuropeptides, neurotransmitters and receptors. Many of our vital needs, such as those for growth, reproduction, nutrition, sleep, and stress responses, depend on hormonal balance or homeostasis, which is controlled by both external and internal stimuli or signals at the hypothalamic level.
The main focus of my laboratory is to understand, at the molecular level, how the hypothalamus achieves its diverse physiological functions. The neuroendocrine hypothalamus consists of a complex array of distinct neuronal phenotypes, each expressing a specific complement of neuropeptides, neurotransmitters and receptors. Many of our vital needs, such as those for growth, reproduction, nutrition, sleep, and stress responses, depend on hormonal balance or homeostasis, which is controlled by both external and internal stimuli or signals at the hypothalamic level.
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AGING CELLno. 2 (2024): e14047-e14047
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2023): 18-26
Endocrinologyno. 9 (2023)
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Brain research (2023): 148367-148367
Journal of neuroendocrinologyno. 5 (2023)
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