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Dr. Le Bihan is especially credited with inventing, developing and introducing into research and clinical practice the concept of diffusion MRI, a new and powerful approach to study normal and diseased brain anatomy and function, as well as brain wiring, from the measurement of molecular motion (Brownian motion), in particular for water, in biological tissues. This method has been taken up by MRI system manufacturers and is today used worldwide both for basic research and clinical applications, especially for the management of acute brain ischemia (stroke), white matter diseases and connectivity disorders, as well as for the diagnosis of cancer (brain, breast, prostate, liver). Noticeably, with Dr.Basser at NIH, Dr Le Bihan introduced Diffusion Tensor Imaging (DTI) which allows to map the circuitry of the brain. This approach is yielding insight into how brain connections underlie brain function, and will open up new lines of inquiry for human neuroscience and for treating brain disorders, especially psychiatric disorders. Dr. Le Bihan has also significantly contributed to the development of functional MRI (fMRI) which has changed for ever the way we study the humain brain, giving access to the neural networks underlying complex cognitive functions, such as language, mental imagery or even consciousness.
研究兴趣
论文共 296 篇作者统计合作学者相似作者
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Nicolas Boulant,Caroline Le Ster,Alexis Amadon, Guy Aubert,Alexander Beckett, Jean Belorgey, Cédric Bonnelye,Dario Bosch, David Otto Brunner,Guillaume Dilasser, Olivier Dubois, Philipp Ehses,
Diffusion MRI of the Breastpp.1-17, (2023)
BJR openno. 1 (2023): 20220038
Magnetic resonance in medicineno. 2 (2023): 428-430
arxiv(2023)
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ENTROPYno. 12 (2023)
Arnaud Cachia,Sidarta Ribeiro, Joan Y. Chiao, Karl Friston, Charles H. Hillman,Adriano Linzarini,Sebastian J. Lipina, Paul Howard-Jones,Jessica Dubois,Therese Jay,Denis Le Bihan, Angel H. Gutchess
Reimagining Education: The International Science and Evidence based Education Assessment (2022)
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