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个人简介
His overarching mission is to translate research from ‘bench to bedside’; to improve understanding of mechanisms that modulate risk vs resilience, and so develop new diagnostic approaches, treatments, and services.
In autism Professor Murphy established the MRC UK AIMS multi centre imaging network – the first in Europe. From this he developed two European Union funded Innovative Medicines Initiatives in autism. The first was called EU-AIMS . The successor to this (EU AIMS-2-TRIALS) (https://www.aims-2-trials.eu/) brings together 48 partners (including academics, charities, autistic individuals and families, regulators and industry) across 14 European countries. The research programme includes a range of studies. These will explore how autism develops, from before birth to adulthood, and how this varies in different people. We will look for biological markers which indicate whether a person has, or may develop, particular characteristics. These markers may help to identify who could ultimately benefit from particular treatments. We will also test treatments. EU AIMS-2-TRIALS links to other groups in North America, South Africa, China, Australia, and Pakistan .
Research Interests
His main interest is in normal brain development, and how abnormalities in this process lead to neurodevelopmental/neuropsychiatric disorders. He supervises PhD Students in
Fetal/neonatal/infant brain development
Brain changes across the lifespan
Risk vs protective mechanisms underpinning the emergence of a variety of neurodevelopmental disorders including autism, ADHD, epilepsy and psychosis. And factors modulating outcome and response to treatment
Disorders of social behaviour in children and adults – e.g. conduct disorder, callous unemotional behaviour, and psychopathy
The impact of specific genetic abnormalities on brain and behaviour
Biomarker discovery and validation.
Treatment trials (including non pharmacological approaches).
Pharmacochallenge studies using brain imaging
In autism Professor Murphy established the MRC UK AIMS multi centre imaging network – the first in Europe. From this he developed two European Union funded Innovative Medicines Initiatives in autism. The first was called EU-AIMS . The successor to this (EU AIMS-2-TRIALS) (https://www.aims-2-trials.eu/) brings together 48 partners (including academics, charities, autistic individuals and families, regulators and industry) across 14 European countries. The research programme includes a range of studies. These will explore how autism develops, from before birth to adulthood, and how this varies in different people. We will look for biological markers which indicate whether a person has, or may develop, particular characteristics. These markers may help to identify who could ultimately benefit from particular treatments. We will also test treatments. EU AIMS-2-TRIALS links to other groups in North America, South Africa, China, Australia, and Pakistan .
Research Interests
His main interest is in normal brain development, and how abnormalities in this process lead to neurodevelopmental/neuropsychiatric disorders. He supervises PhD Students in
Fetal/neonatal/infant brain development
Brain changes across the lifespan
Risk vs protective mechanisms underpinning the emergence of a variety of neurodevelopmental disorders including autism, ADHD, epilepsy and psychosis. And factors modulating outcome and response to treatment
Disorders of social behaviour in children and adults – e.g. conduct disorder, callous unemotional behaviour, and psychopathy
The impact of specific genetic abnormalities on brain and behaviour
Biomarker discovery and validation.
Treatment trials (including non pharmacological approaches).
Pharmacochallenge studies using brain imaging
研究兴趣
论文共 845 篇作者统计合作学者相似作者
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Johanna Leyhausen,Tim Schaefer, Caroline Gurr, Lisa M. Berg,Hanna Seelemeyer,Charlotte M. Pretzsch,Eva Loth,Bethany Oakley,Jan K. Buitelaar,Christian F. Beckmann,Dorothea L. Floris,Tony Charman,
European Urologyno. 2 (2024): e60-e61
Alice Thomson, Carlotta Castillo, Henrike Graefen,Sachin Perera,Nathan Lawrentschuk,Marlon Perera,Renu Eapen,Declan G. Murphy
European Urology (2024)
Haidar Al Saffar,David C. Chen, Carlos Delgado, Jacob Ingvar,Michael S. Hofman,Nathan Lawrentschuk,Marlon Perera,Declan G. Murphy,Renu Eapen
CANCERSno. 5 (2024): 939
Jianliang Liu, Jordan Santucci,Dixon T. S. Woon, Rick Catterwell,Marlon Perera,Declan G. Murphy,Nathan Lawrentschuk
LIFE-BASELno. 1 (2024): 76
David C. Chen, Haidar AlSaffar, Henrike Graefen,Sachin Perera, Elio Mazzone,Marlon L. Perera,Nathan Lawrentschuk,Declan G. Murphy
European Urology (2024)
Alice Thomson, Carlotta Castillo, Henrike Graefen,Sachin Perera,Nathan Lawrentschuk,Marlon Perera,Renu Eapen,Declan G Murphy
European urology (2024)
BJUI COMPASSno. 1 (2024): 121-141
Bethany Oakley,Charlotte Boatman,Sophie Doswell, Antonia Dittner, Andrew Clarke,Ann Ozsivadjian,Rachel Kent, Adrian Judd,Saffron Baldoza, Amy Hearn,Declan Murphy,Emily Simonoff
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