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David Sidransky, M.D. is a leading expert and pioneer in the molecular genetic detection of cancer. He is the Director of Head and Neck Cancer Research in the Department of Otolaryngology- Head and Neck Surgery at Johns Hopkins University and a member of the Johns Hopkins Kimmel Cancer Center. David Sidransky M.D. is best known for in research in biomarkers for early detection and therapy. Currently, his research is concentrating on identifying new genetic and epigenetic changes on smoking-associated tumors, including lung cancer, head and neck cancer and bladder cancer. His laboratory group is also investigating the molecular epidemiology of smoking induced cancers and the link between tobacco smoke and mutations of critical oncogenes (genes that when altered, can cause cancer). His group develops new human models called tumor grafts that help accelerate drug development and help isolate predictive markers for personalized cancer therapy.
Dr. Sidransky received his medical degree from Baylor College of Medicine in 1984, where he also completed a residency in internal medicine. He came to Johns Hopkins in 1988, where he completed a clinical and research fellowship in oncology. Dr. Sidransky joined the Hopkins faculty in 1992. He has over 500 peer-reviewed publications, and has contributed more than 65 cancer reviews and chapters and also has numerous issued biotechnology patents based on detection of genetic biomarkers for cancer in many bodily fluids. These tests are being studied in bladder, lung, and head and neck cancers, to detect malignant cells in a very early stage, before they can be identified by conventional pathology and cytology methods. These same biomarkers have been instrumental in differentiating normal tissue from malignant tissue in head and neck cancer surgery.
He has been the recipient of many other awards and honors, including the 1997 Sarstedt International prize from the German society of clinical Chemistry, the 1998 Alton Ochsner Award Relating Smoking and Health by the American College of Chest Physicians and the Richard and Hinda Rosenthal Foundation Award of the American Association of Cancer Research (AACR) for this work.
Dr. Sidransky received his medical degree from Baylor College of Medicine in 1984, where he also completed a residency in internal medicine. He came to Johns Hopkins in 1988, where he completed a clinical and research fellowship in oncology. Dr. Sidransky joined the Hopkins faculty in 1992. He has over 500 peer-reviewed publications, and has contributed more than 65 cancer reviews and chapters and also has numerous issued biotechnology patents based on detection of genetic biomarkers for cancer in many bodily fluids. These tests are being studied in bladder, lung, and head and neck cancers, to detect malignant cells in a very early stage, before they can be identified by conventional pathology and cytology methods. These same biomarkers have been instrumental in differentiating normal tissue from malignant tissue in head and neck cancer surgery.
He has been the recipient of many other awards and honors, including the 1997 Sarstedt International prize from the German society of clinical Chemistry, the 1998 Alton Ochsner Award Relating Smoking and Health by the American College of Chest Physicians and the Richard and Hinda Rosenthal Foundation Award of the American Association of Cancer Research (AACR) for this work.
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