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David Kritchevsky was not a member of the epidemiological community but appears on this history website because he was one of the first cardiovascular disease investigators to explore the relationship of serum lipids and atherosclerosis. He tended to observe epidemiological efforts in the field of diet and lipids and coronary disease with a bemused wisdom and quiet skepticism.
He traced the relationship of cholesterol to atherosclerosis from the 1840s’ work of Vogel on free and esterified cholesterol excess in arterial plaques, to the classic Russian experimental pathology in the early 20th century, feeding pure cholesterol, and indicated how that opened a floodgate for the still-continuing investigations of lipid feeding and diet. He importantly attacked the idea that atherosclerosis cannot be experimentally produced in carnivores as no argument against its importance in humans. He gives credit to Rosenthal for the first clear statement in 1934 that “no ethnic group subsisting on a cholesterol-rich diet is free of atherosclerosis”(ibid.).
With his vast understanding of the chemistry, physiology, anatomy, and pathology of “cholesterol,” and with his critical mind and skills at satire, Kritchevsky was for many decades an effective as well as charming and amusing analyst of “diet-heart” ideas. He may never have arrived at a full “population view” of coronary disease but he assimilated and synthesized the epidemiological evidence better than other bench scientists. Some of us were privileged to hear his satirical renderings on the subject of cholesterol and culture in the form of delightful doggerel, accompanied by barrelhouse piano, with which he amused intimates over the years.
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Nutrition and Disease PreventionSoy in Health and Disease Preventionpp.289-297, (2005)
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