David Koditek - Gilead Sciences | 人才画像

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David Koditek currently works at the Department of Biology, Gilead Sciences. David does research in Biochemistry, Cell Biology and Molecular Biology. Their most recent publication is 'Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability'.

Research Interests

Papers共 13 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Discovery of an Atropisomeric PI3Kβ Selective Inhibitor Through Optimization of the Hinge Binding Motif

Stephane Perreault, Fatima Arjmand,Jayaraman Chandrasekhar,Jia Hao,Kathleen S. Keegan,David Koditek,Eve-Irene Lepist,Clinton K. Matson,Mary E. McGrath,Leena Patel,Kassandra Sedillo,Joseph Therrien,Nicholas A. Till,Adrian Tomkinson,Jennifer Treiberg,Yelena Zherebina,Gary Phillips

ACS Medicinal Chemistry Letters（2020）

Cited11Views0WOSBibtex

Clinical targeting of HIV capsid protein with a long-acting small molecule

John O. Link,Martin S. Rhee,Winston C. Tse,Jim Zheng,John R. Somoza,William Rowe,Rebecca Begley,Anna Chiu,Andrew Mulato,Derek Hansen, Eric Singer,Luong K. Tsai,Rujuta A. Bam,Chien-Hung Chou,Eda Canales,Gediminas Brizgys,Jennifer R. Zhang,Jiayao Li,Michael Graupe,Philip Morganelli,Qi Liu,Qiaoyin Wu,Randall L. Halcomb,Roland D. Saito,Scott D. Schroeder,Scott E. Lazerwith,Steven Bondy,Debi Jin,Magdeleine Hung,Nikolai Novikov,Xiaohong Liu,Armando G. Villaseñor,Carina E. Cannizzaro,Eric Y. Hu, Robert L. Anderson,Todd C. Appleby,Bing Lu,Judy Mwangi,Albert Liclican,Anita Niedziela-Majka,Giuseppe A. Papalia,Melanie H. Wong,Stephanie A. Leavitt,Yili Xu,David Koditek,George J. Stepan,Helen Yu,Nikos Pagratis,Sheila Clancy,Shekeba Ahmadyar, Terrence Z. Cai,Scott Sellers, Scott A. Wolckenhauer,John Ling,Christian Callebaut,Nicolas Margot,Renee R. Ram,Ya-Pei Liu, Rob Hyland,Gary I. Sinclair,Peter J. Ruane,Gordon E. Crofoot,Cheryl K. McDonald,Diana M. Brainard,Latesh Lad,Swami Swaminathan,Wesley I. Sundquist,Roman Sakowicz,Anne E. Chester, William E. Lee,Eric S. Daar,Stephen R. Yant,Tomas Cihlar

Nature（2020）

Cited331Views0WOSNATUREBibtex

331

Gs-4361: A Novel Ido1 Inhibitor

Rao Kalla, Kristy Elbel, Mark Bartlett,Jennifer Cosman,Thao Perry,Elfatih Elzein,Xiaofen Li,Dmitry Koltun,Eric Parkhill,Jeff Zablocki, Mike Clark, Heather Maecker,Sudhamsu Jawahar, Deborah Hendricks, Alex Shornikov,David Koditek,Brian Stafford,Daniel Soohoo,Johannes Voigt,Eric Lansdon,Richard Mackman,Britton Corkey

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2019）

Cited0Views0Bibtex

Highly Delta Selective Quinazolinone Pi3k Inhibitors

Jennifer Treiberg,Jayaraman Chandrasekhar,Carmen Ip,David Koditek,Eve-Irene Lepist,Mary Mcgrath,Judy Mwangi,Stephane Perreault,John Somoza,Bart Steiner,Joseph Therrien,Armando Villasenor,Sarah Wise,Belinda Wong,Gary Phillips

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2018）

Cited0Views0Bibtex

Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) Β Inhibitor

Jayaraman Chandrasekhar,Ryan Dick, Joshua Van Veldhuizen,David Koditek,Eve-Irene Lepist,Mary E. McGrath,Leena Patel,Gary Phillips,Kassandra Sedillo,John R. Somoza,Joseph Therrien,Nicholas A. Till,Jennifer Treiberg,Armando G. Villasenor,Yelena Zherebina,Stephane Perreault

JOURNAL OF MEDICINAL CHEMISTRY（2018）

Cited45Views0WOSBibtex

Functional Label-Free Assays for Characterizing the in Vitro Mechanism of Action of Small Molecule Modulators of Capsid Assembly

Latesh Lad,Sheila Clancy,David Koditek,Melanie H. Wong,Debi Jin,Anita Niedziela-Majka,Giuseppe A. Papalia,Magdeleine Hung,Stephen Yant,John R. Somoza,Eric Hu,Chienhung Chou,Winston Tse,Randall Halcomb,Roman Sakowicz,Nikos Pagratis

Biochemistry（2015）

Cited8Views0WOSBibtex

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase Δ*

John R. Somoza,David Koditek,Armando G. Villasenor,Nikolai Novikov,Melanie H. Wong,Albert Liclican,Weimei Xing,Leanna Lagpacan,Ruth Wang,Brian E. Schultz,Giuseppe A. Papalia,Dharmaraj Samuel,Latesh Lad,Mary E. McGrath

Journal of Biological Chemistry（2015）

Cited136Views0WOSBibtex

136

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