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个人简介
My principal research interests are the etiology of cancer, particularly breast, prostate, pancreas and skin cancers. I am an investigator on the Nurses’ Health Study, a long-running cohort of 121,000 US women, and was project director for the Nurses’ Health Study II, a newer cohort of 116,000 women. I founded the Pooling Project of Diet and Cancer, a collaborative analysis of dietary risk factors for breast, colorectal and lung cancers. I analyze inherited susceptibility to cancer and other chronic diseases using genetic analyses. This work is largely based in subcohorts of the Nurses Health Study and the Health Professionals Follow-up Study of approximately 50,000 women and 25,000 men who have given a blood or saliva sample that can be used for DNA analyses. I have led collaborative analysis across large Consortia, leading to the discovery of multiple genetic associations including the common genetic variant in FGFR2 with the strongest association with breast cancer. I developed and supervised laboratories at the Harvard Chan School of Public Health in which gene sequence information from these samples is obtained.
I have also studied HIV transmission for over twenty-five years, initially in Kenya and then in Tanzania. I have collaborated with investigators in Dar-es-Salaam to understand the relationship of nutritional status with progression of HIV disease and perinatal transmission.
I co-chaired the Steering Committee of the NCI Breast and Prostate Cancer Cohort Consortium, was co-Director of the NCI Cancer Genetic Markers of Susceptibility (CGEMS) Special Initiative, and was a member of the Board of Scientific Counselors of the National Cancer Institute. I am contact Principal Investigator of the DRIVE (Discovery, Biology and Risk of Inherited Variants in Breast Cancer) Consortium. According to Thomson Reuters I am one of approximately 3,000 highly cited researchers in all branches of science worldwide. I am the author of over 700 peer-reviewed articles and commentaries, and have co-edited three books, most recently Readings in Global Health (Oxford University Press).
I have also studied HIV transmission for over twenty-five years, initially in Kenya and then in Tanzania. I have collaborated with investigators in Dar-es-Salaam to understand the relationship of nutritional status with progression of HIV disease and perinatal transmission.
I co-chaired the Steering Committee of the NCI Breast and Prostate Cancer Cohort Consortium, was co-Director of the NCI Cancer Genetic Markers of Susceptibility (CGEMS) Special Initiative, and was a member of the Board of Scientific Counselors of the National Cancer Institute. I am contact Principal Investigator of the DRIVE (Discovery, Biology and Risk of Inherited Variants in Breast Cancer) Consortium. According to Thomson Reuters I am one of approximately 3,000 highly cited researchers in all branches of science worldwide. I am the author of over 700 peer-reviewed articles and commentaries, and have co-edited three books, most recently Readings in Global Health (Oxford University Press).
研究兴趣
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ARTHRITIS CARE & RESEARCHno. 2 (2024): 208-224
The Journal of orthopaedic and sports physical therapyno. 5 (2023): 236-238
Arthritis Research & Therapyno. 1 (2023): 1-11
NEW ENGLAND JOURNAL OF MEDICINEno. 13 (2023): 1211-1219
medRxiv (Cold Spring Harbor Laboratory) (2023)
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