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个人简介
My research efforts over the past decade have evolved into several programs that are distinct in focus, yet coalesce into an overriding theme that include molecular genetic, biochemical and bioorganic chemical studies of microbial natural product biosynthesis. Metabolic engineering and combinatorial biosynthesis are powerful approaches for harnessing the tremendous metabolic capabilities of microorganisms, including primary and secondary pathways. New genomic-based technologies are enhancing considerably our ability to understand and manipulate complex biosynthetic systems and will enable vast new opportunities in medicine and industry. My laboratory is exploring fundamental aspects of the systems described below, as well as pursuing drug discovery opportunities in the area of infectious diseases and cancer.
研究兴趣
论文共 603 篇作者统计合作学者相似作者
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crossref(2024)
Morgan McCauley, Matthew Huston, Alanna R. Condren, Filipa Pereira, Joel Cline, Marianne Yaple-Maresh,Mark M. Painter, Gretchen E. Zimmerman,Andrew W. Robertson, Nolan Carney, Christopher Goodall,Valeri Terry,
Michael R. Rankin,Dheeraj Khare, Estefania Martinez Valdivia,David H. Sherman,William H. Gerwick, Anna K. Mapp,Janet L. Smith
Acta Crystallographicano. a1 (2023): A194-A194
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Applied and Environmental Microbiologyno. 5 (2023)
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Maribel E.K. Okiye, Michelle Velez,Janet S. Kinney,James V. Sugai,William V. Giannobile,Ashootosh Tripathi,David H. Sherman
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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ADVANCED SYNTHESIS & CATALYSIS (2023)
Zhiwen Liu, Sebastian Rivera,Sean A. Newmister,Jacob N. Sanders,Qiuyue Nie,Shuai Liu,Fanglong Zhao,Joseph D. Ferrara, Hao-Wei Shih, Siddhant Patil,Weijun Xu,Mitchell D. Miller,
Alexander Rittner,Mirko Joppe,Jennifer J. Schmidt, Lara Maria Mayer, Simon Reiners,Elia Heid, Dietmar Herzberg,David H. Sherman,Martin Grininger
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