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His research includes investigating the influence of specific genes such as those involved in cell-to-cell communication on the production of the matrix polymer material that is responsible for cementing biofilm bacteria to surfaces and for maintaining the integrity of the biofilm architecture. He also researches the mechanisms by which Pseudomonas biofilms are "autodispersed" in an effort to develop methods by which biofilm disruption can be reproducibly induced. The disruption of biofilms is of major importance in medicine where treatment of biofilm infections has proved to be generally ineffective. In another area of his research, he looks at the protein profile or "proteome" of the bacteria during the biofilm developmental process in order to characterize the phenotypic changes that are experienced by the bacteria and to help reveal targets for agents that will interfere with normal biofilm development.
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MBIOno. 6 (2023): e0257023-e0257023
Anaerobic Fungipp.107-128, (2020)
semanticscholar(2016)
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