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His early studies in the 1980s used specific bacterial lipids as a fingerprint to identify and group bacteria, in particular antibiotic-producing bacteria. In 1982, he described the waxy coat of unusual lipids and sugars around the tuberculosis organism, which provided a shield against common antibiotics. His subsequent studies based on “the Minnkin model” identified several new drugs that would weaken this shield, thereby shaping efforts in drug discovery against tuberculosis. This is recognised as a landmark in mycobacterial research – and all carried out before the era of genomics.
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Tuberculosis (Edinburgh, Scotland) (2023): 102420-102420
Tuberculosis (Edinburgh, Scotland) (2023): 102419-102419
Access Microbiologyno. 7A (2020)
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