His research interests include the epidemiology and prevention of heart disease and stroke with a focus on issues related to high blood pressure, diabetes, and dyslipidemia. He has published over 300 manuscripts, book chapters, and other scientific reports. He has served in a variety of leadership roles in multiple NIH-, CDC-, and AHA-funded studies and committees. He has directed the Ten-Day Seminar on the Epidemiology and Prevention of Cardiovascular Disease since 2000. He has served as a member of the Board of Directors for the Association of Schools and Programs of Public Health, President of the Board of Directors for the Denver Metro Division of the American Heart Association, Chair of the Council on Epidemiology and Prevention for the American Heart Association, and Chair of the Council on Quality of Care and Outcomes Research for the American Heart Association.