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职业迁徙
个人简介
We saw 800 brain tumor referrals and conducted 10-15 clinical trials annually. I also led the in vivo preclinical testing program which included 100 established CNS tumor cell lines and 50-60 patient-derived primary tumor xenografts. Each year we evaluated 50-75 investigational compounds for anti-tumor activity in flank and orthotopic, intracranial human brain tumor models. Via this effort, we successfully transitioned several preclinical compounds into clinical trials for brain tumor patients. I co-authored over 100 peer-reviewed manuscripts, was awarded an R21 NIH grant, and served as principal investigator of clinical core sections of an awarded brain SPORE grant and two program project grants. I also conducted several noteworthy, multi-center phase I-II clinical trials for neuro-oncology patients, two of which led to pivotal phase III studies evaluating cilengitide, as well as imatinib plus hydroxyurea, respectively, for glioblastoma. I also taught 1-3 neuro-oncology fellows per year who were supported through a NCI T-32 award. My clinical and research efforts at Duke were recognized by receipt of the R. K Rundles Award for Excellence in Clinical Oncology Research in 2007.
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论文共 797 篇作者统计合作学者相似作者
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Neuro-oncologyno. 2 (2024): 211-225
Yu-Han Hung, Aparna Chhibber,Michael Lim,Michael Weller,David A. Reardon,Antonio Omuro, Keith L. Ligon, Ana Lako, Ann Forslund
Cancer Researchno. 7_Supplement (2024)
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2024): 100697-100697
The Lancet. Oncologyno. 8 (2023): 925-935
NEURO-ONCOLOGY (2023)
FRONTIERS IN IMMUNOLOGYno. 7 (2023): 1297932-1297932
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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medRxiv (Cold Spring Harbor Laboratory) (2023)
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David A. Reardon,Liam Welsh,Kent C. Shih, Toshio Shimizu, Jean-Charles Goeminne,Birgit Geoerger,Capucine Baldini,Christophe Massard,Yohann Loriot,Shubham Pant,Sameer Farouk Sait,Shibu Thomas,
Neuro-oncologyno. Supplement_5 (2023): v91-v91
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