基本信息
浏览量:81
职业迁徙
个人简介
The focus of Dr. Hess’ research is to understand the mechanisms by which distinct stem cell subsets co-ordinate hematopoiesis, angiogenesis, and tissue repair. Ultimately, Dr. Hess is interested in the development of cellular therapies to mediate the repair of diseased, damaged, or ischemic tissues. Specific applications for his work include the use of transplanted human stem cells to promote wound healing and blood vessel formation, and to regenerate insulin-producing beta cells during diabetes.
In an attempt to isolate and study the regenerative functions of human bone marrow-derived stem cells, Dr. Hess' lab has purified multiple (hematopoitic, endothelial, and mesenchymal) stem cell lineages simultaneously using high-speed fluorescence activated cell sorting based on a conserved stem cell function (high aldehyde dehydrogenase activity) and cell surface markers. These progenitor cell lineages can be expanded efficiently in vitroand their regenerative functions are studied by the transplantation in immune deficient mouse models specifically designed to track the contributions of human cells during blood vessel formation during critical limb ischemia, and during the regeneration of islet function in hyperglycemic recipients
In an attempt to isolate and study the regenerative functions of human bone marrow-derived stem cells, Dr. Hess' lab has purified multiple (hematopoitic, endothelial, and mesenchymal) stem cell lineages simultaneously using high-speed fluorescence activated cell sorting based on a conserved stem cell function (high aldehyde dehydrogenase activity) and cell surface markers. These progenitor cell lineages can be expanded efficiently in vitroand their regenerative functions are studied by the transplantation in immune deficient mouse models specifically designed to track the contributions of human cells during blood vessel formation during critical limb ischemia, and during the regeneration of islet function in hyperglycemic recipients
研究兴趣
论文共 204 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Aishwarya Krishnaraj,Ehab Bakbak,Hwee Teoh,Yi Pan, Irene N. Firoz,Arjun K. Pandey,Daniella C. Terenzi,Raj Verma,Basel Bari, Asaad I. Bakbak, Shakkeela Padanilathu Kunjummar,Bobby Yanagawa,
Journal of the American College of Cardiologyno. 7 (2024): 755-769
Daniella C Terenzi,Ehab Bakbak,Hwee Teoh, Aishwarya Krishnaraj,Pankaj Puar,Ori D Rotstein,Francesco Cosentino, Ronald M Goldenberg,Subodh Verma,David A Hess
Cardiovascular researchno. 18 (2024): 2858-2874
Brady Park,Ehab Bakbak,Hwee Teoh, Aishwarya Krishnaraj, Fallon Dennis,Adrian Quan,Ori D Rotstein,Javed Butler,David A Hess,Subodh Verma
American journal of physiology. Heart and circulatory physiology (2024)
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGYno. 5 (2023): H1210-H1222
Aishwarya Krishnaraj,Ehab Bakbak,Hwee Teoh,Deepak L Bhatt,Adrian Quan,Pankaj Puar,Bhaavani Lambotharan,Aathmika Kirubaharan, Irene N Firoz,Gus Meglis,Bobby Yanagawa,Basel Bari,
Med (New York, N.Y.)no. 2 (2023): 130-138.e1
crossref(2023)
Daniela F. Quail,Logan A. Walsh,Guihua Zhang,Scott D. Findlay,Juan Moreno, Laura Fung, Amber Ablack,John D. Lewis,Susan J. Done,David A. Hess,Lynne-Marie Postovit
crossref(2023)
Daniela F. Quail,Logan A. Walsh,Guihua Zhang,Scott D. Findlay,Juan Moreno, Laura Fung, Amber Ablack,John D. Lewis,Susan J. Done,David A. Hess,Lynne-Marie Postovit
crossref(2023)
Francesco Cosentino,Subodh Verma,Philip Ambery,Marianne Bach Treppendahl, Martin van Eickels,Stefan D Anker, Michele Cecchini,Paola Fioretto,Per-Henrik Groop,David Hess,Kamlesh Khunti,Carolyn S P Lam,
引用0浏览0WOS引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn