基本信息
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个人简介
His laboratory has received funding support from NIH, DoD, JDRF and American Diabetes Association. Danny has received recognitions including an American Peptide Society Early Career Lectureship, Boulder Peptide Society Young Investigator Award, JDRF Career Development Award, Vertex Scholar, JDRF Postdoctoral Fellow and ADA Junior Faculty Award.
Current Research and Scholarly Interests
Our research program integrates concepts of chemical biology, protein engineering and structure biology to design new therapeutic leads and generate probes to study biological processes. A key focus of our lab is insulin, an essential hormone in our body to reduce blood glucose levels. We generate synthetic libraries of insulin analogs to select for chemical probes, and investigate natural insulin molecules (e.g. from the venom of fish-hunting cone snails!) to develop novel therapeutic candidates. We are especially interested in using chemical and enzymatic synthesis to create novel chemical entities with enhanced properties, and leverage the strong expertise of our collaborators to apply our skill sets in the fields of cancer biology, immunology and pain research. Our ultimate goal is to translate our discovery into therapeutic interventions in human diseases.
Current Research and Scholarly Interests
Our research program integrates concepts of chemical biology, protein engineering and structure biology to design new therapeutic leads and generate probes to study biological processes. A key focus of our lab is insulin, an essential hormone in our body to reduce blood glucose levels. We generate synthetic libraries of insulin analogs to select for chemical probes, and investigate natural insulin molecules (e.g. from the venom of fish-hunting cone snails!) to develop novel therapeutic candidates. We are especially interested in using chemical and enzymatic synthesis to create novel chemical entities with enhanced properties, and leverage the strong expertise of our collaborators to apply our skill sets in the fields of cancer biology, immunology and pain research. Our ultimate goal is to translate our discovery into therapeutic interventions in human diseases.
研究兴趣
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ACS CHEMICAL BIOLOGYno. 2 (2024): 506-515
Wenchao Li,Michael T. Jacobsen, Claire Park, Jae Un Jung,Nai-Pin Lin,Po-Ssu Huang, Rayhan A. Lal,Danny Hung-Chieh Chou
CHEMICAL SCIENCEno. 9 (2024): 3214-3222
Chembiochem : a European journal of chemical biologyno. 24 (2023): e202300470-e202300470
Organic & biomolecular chemistryno. 44 (2023): 8902-8909
Claire Park,Yanxian Zhang, Jae Un Jung, Line Due Buron,Nai-Pin Lin,Thomas Hoeg-Jensen,Danny Hung-Chieh Chou
Acta Pharmaceutica Sinica Bno. 5 (2023): 2281-2290
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