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Daniela Rhodes has made many fundamental contributions to understanding the structure and function of nucleic acids and their biologically important interactions with many different proteins. Her work combines biochemical analyses with direct structural determination. She determined the structures of a number of important protein-DNA complexes involved in transcription, such as zinc-fingers and nuclear hormone receptors. She has provided some of the first structural information on telomeric proteins, such as yeast Rap1p and human TRF1 and TRF2 and their complexes with DNA. Throughout her career she has made many contributions to the understanding of chromatin structure and function. She was involved in determining the structure of the nucleosome core particle, has worked on transcriptionally active chromatin and more recently on the higher order 30nm structure of chromatin. Her research continues to focus on understanding how the structure of chromatin is involved in transcriptional regulation and how telomeres are involved in preserving chromosome integrity.
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论文共 176 篇作者统计合作学者相似作者
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Communications Biologyno. 1 (2024): 1-12
Martin Law,Sofia Villar,Nicholas Oscroft, Victoria Stoneman,Julia Fox-Rushby,Yi-Da Chiu,Jo Steele,Thomas Devine, Claire Francis, Thomas Claydon, Graham Hill,Ka Keat Lim,
Trialsno. 1 (2023): 1-14
Trialsno. 1 (2023): 1-5
RSC CHEMICAL BIOLOGYno. 12 (2023): 1096-1110
Aghil Soman, Sook Yi Wong,Nikolay Korolev, Wahyu Surya, Simon Lattman,Vinod K. Vogirala,Qinming Chen,Nikolay V. Berezhnoy,John van Noort,Daniela Rhodes,Lars Nordenskiöld
crossref(2022)
biorxiv(2022)
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