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DNA replication and repair; nucleic acid chemistry
The Semlow lab, uses complementary biochemical, genetic, and analytical approaches to understand the mechanisms that allow cells to tolerate and repair DNA damage during replication. Furthermore, the lab develops tools to identify novel forms of chemical DNA damage and elucidate the origin of these lesions. Beyond advancing current understanding of critical DNA repair pathways, these studies may form the basis of therapeutic interventions that sensitize cancer cells to chemotherapy or mitigate the effects of disease-causing DNA repair deficiencies.
DNA replication and repair; nucleic acid chemistry
The Semlow lab, uses complementary biochemical, genetic, and analytical approaches to understand the mechanisms that allow cells to tolerate and repair DNA damage during replication. Furthermore, the lab develops tools to identify novel forms of chemical DNA damage and elucidate the origin of these lesions. Beyond advancing current understanding of critical DNA repair pathways, these studies may form the basis of therapeutic interventions that sensitize cancer cells to chemotherapy or mitigate the effects of disease-causing DNA repair deficiencies.
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论文共 15 篇作者统计合作学者相似作者
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Maria Altshuller, Xu He, Elliot J MacKrell,Kevin M Wernke, Joel W H Wong, Selene Sellés-Baiget,Ting-Yu Wang,Tsui-Fen Chou,Julien P Duxin,Emily P Balskus,Seth B Herzon,Daniel R Semlow
bioRxiv : the preprint server for biology (2024)
Selene Selles-Baiget, Sara Marie Ambjorn, Alberto Carli,Ivo A Hendriks,Irene Gallina,Norman E Davey,Bente Benedict, Bob Meeusen,Emil P.T. Hertz, Laura Slappendel,Daniel Semlow, Sampath A Gadi,
biorxiv(2023)
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Maximilian Donsbach,Sophie Dürauer, Florian Grünert,Kha T Nguyen, Richa Nigam,Denitsa Yaneva,Pedro Weickert,Rachel Bezalel-Buch,Daniel R Semlow,Julian Stingele
The EMBO journalno. 18 (2023)
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Maximilian Donsbach,Sophie Dürauer,Kha T. Nguyen, Florian Grünert,Denitsa Yaneva,Daniel Semlow,Julian Stingele
biorxiv(2022)
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