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个人简介
Daniel studied mathematics (BSc, Leicester) and medical statistics (MSc, Leicester) before working as a statistician at the MRC Epidemiology Unit (Cambridge). He then studied genetic epidemiology (PhD, Cambridge) under the supervision of Prof Antonis Antoniou, focusing on the development and application of statistical methods to analyse the associations between genetic variants and disease risk under non-random sampling designs at the Centre for Cancer Genetic Epidemiology (CCGE). This work was motivated by women with mutations in BRCA1 and BRCA2 and women considered at high-risk of developing disease because of a strong family history. Immediately before rejoining CCGE, Daniel worked as a Research Associate statistician (genetics) at the Cardiovascular Epidemiology Unit, University of Cambridge. In this role he worked on genetic association studies and pathway analyses, applying these methods to analyses genetic causes of cardiovascular disease and related traits.
Research Interests
Daniel’s current research interests are statistical analyses of BRCA1 and BRCA2 gene mutation carriers, primarily through data obtained by the CIMBA consortium. These individuals are at increased risk of breast cancer and ovarian cancer in women, and breast cancer and prostate cancer in men. Analyses that Daniel is particularly interested in are genome-wide association analyses, fine-mapping, polygenic risk scores, gene-based testing and pathway analyses.
Research Interests
Daniel’s current research interests are statistical analyses of BRCA1 and BRCA2 gene mutation carriers, primarily through data obtained by the CIMBA consortium. These individuals are at increased risk of breast cancer and ovarian cancer in women, and breast cancer and prostate cancer in men. Analyses that Daniel is particularly interested in are genome-wide association analyses, fine-mapping, polygenic risk scores, gene-based testing and pathway analyses.
研究兴趣
论文共 59 篇作者统计合作学者相似作者
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user-5f8cf9244c775ec6fa691c99(2022)
JNCI: Journal of the National Cancer Instituteno. 1 (2021): 109-122
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Vivek L Patel,Evan L Busch,Tara M Friebel,Angel Cronin,Goska Leslie,Lesley McGuffog,Julian Adlard,Simona Agata,Bjarni A Agnarsson,Munaza Ahmed,Kristiina Aittomäki, Elisa Alducci,
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