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个人简介
Dr. Brat directs a basic and translational research lab that investigates mechanisms of glioma progression, including the contributions of hypoxia, genetics, tumor microenvironment and stem cells. Glioma progression is characterized by tumor necrosis, severe hypoxia and angiogenesis. One project investigates mechanisms that cause hypoxia and has focused on vaso-occlusion and intravascular thrombosis that are thought to be initiated by tissue factor, a highly potent pro-coagulant. His lab is studying how the reshaping of the tumor micro-environment leads to accelerated tumor growth and how the enrichment of glioma stem cells and influx of tumor associated macrophages may promote this.
研究兴趣
论文共 404 篇作者统计合作学者相似作者
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Cancer research (2024)
Brain Pathology (2024)
Subhas Mukherjee,Carol Tucker-Burden,Changming Zhang,Kenneth Moberg,Renee Read, Costas Hadjipanayis,Daniel J. Brat
crossref(2023)
Alexander S. Chen,Joanna Wardwell-Ozgo, Nilang N. Shah, Deidre Wright,Christina L. Appin,Krishanthan Vigneswaran,Daniel J. Brat,Harley I. Kornblum,Renee D. Read
crossref(2023)
Victor Karwacinski,Tatiana Carneiro-Lobo,Cheryl L. Olson, Marco Constante,Pinar Mesci,Daniel J. Brat,Alysson R. Muotri
Neuro-oncologyno. Supplement_5 (2023): v283-v284
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crossref(2023)
Yuan Rong, Vladimir E. Belozerov,Carol Tucker-Burden, Gang Chen,Donald L. Durden, Jeffrey J. Olson,Erwin G. Van Meir,Nigel Mackman,Daniel J. Brat
crossref(2023)
Giulia Fulci,Nina Dmitrieva,Davide Gianni, Elisabeth J. Fontana,Xiaogang Pan,Yanhui Lu, Claire S. Kaufman,Balveen Kaur,Sean E. Lawler,Robert J. Lee,Clay B. Marsh,Daniel J. Brat,
crossref(2023)
Subhas Mukherjee,Carol Tucker-Burden,Changming Zhang,Kenneth Moberg,Renee Read, Costas Hadjipanayis,Daniel J. Brat
crossref(2023)
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Incno. 11 (2023): 100294-100294
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