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职业迁徙
个人简介
Dan Hertz joined the Department of Clinical Pharmacy in the College of Pharmacy in April 2013. He received his PharmD from the Ernest Mario School of Pharmacy at Rutgers University and his PhD in pharmaceutical sciences from the University of North Carolina Eshelman School of Pharmacy.
Interested in developing tools for individualizing cancer treatment, his current work focuses on the optimal use of paclitaxel in breast cancer. The approaches being developed include identifying an ideal exposure target to maximize efficacy while avoiding unnecessary toxicity, particularly as it relates to neuropathy. Hertz is also interested in understanding the influence of patient genetics on cancer treatment outcomes. He uses several approaches to discover and validate the effect of common variants on drug exposure or patient sensitivity to toxicity. Much of this work is conducted through his membership in oncology cooperative groups, which provide access to sufficiently large patient cohorts for definitive analyses.
Interested in developing tools for individualizing cancer treatment, his current work focuses on the optimal use of paclitaxel in breast cancer. The approaches being developed include identifying an ideal exposure target to maximize efficacy while avoiding unnecessary toxicity, particularly as it relates to neuropathy. Hertz is also interested in understanding the influence of patient genetics on cancer treatment outcomes. He uses several approaches to discover and validate the effect of common variants on drug exposure or patient sensitivity to toxicity. Much of this work is conducted through his membership in oncology cooperative groups, which provide access to sufficiently large patient cohorts for definitive analyses.
研究兴趣
论文共 181 篇作者统计合作学者相似作者
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Jai N. Patel,Chen Jiang,Kouros Owzar,Daniel L. Hertz,Janey Wang, Flora A. Mulkey,William K. Kelly,Susan Halabi,Yoichi Furukawa, Cameron Lassiter,Susan G. Dorsey,Paula N. Friedman,
The Pharmacogenomics Journalno. 2 (2024): 1-8
CLINICAL PHARMACOLOGY & THERAPEUTICSno. 3 (2024): 452-456
JAMIA OPENno. 1 (2024): ooae006-ooae006
European Journal of Cancer (2024): 114024-114024
Daniel L Hertz,Chad A Bousman,Howard L McLeod,Andrew A Monte,Deepak Voora, Lori A Orlando, Rustin D Crutchley,Benjamin Brown, Wrenda Teeple,Sara Rogers,Jai N Patel
Anna M. McLaughlin,Thomas Helland, Fenja Klima,Stijn L. W. Koolen, Ron H. N. van Schaik,Ron H. J. Mathijssen,Patrick Neven,Jesse J. Swen,Henk-Jan Guchelaar, Florence Dalenc,Melanie White-Koning,Robin Michelet,
CLINICAL PHARMACOLOGY & THERAPEUTICS (2024)
Nathan D Seligson,Jill M Kolesar, Benish Alam, Laura Baker,Jatinder K Lamba,Brooke L Fridley,Ameen A Salahudeen,Daniel L Hertz,J Kevin Hicks
Pharmacogenomicsno. 13 (2023): 731-738
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CANCER RESEARCHno. 5 (2023)
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Amy L Pasternak, Robinson Seda, Joseph Lipa,Rachel L McDevitt,Oxana V Crysler,Paul L Swiecicki, Bryan J Schneider,Brett Vanderwerff,N Lynn Henry,John C Krauss,Vaibhav Sahai,Daniel L Hertz
Clinical pharmacology and therapeuticsno. 2 (2023): 356-361
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