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Tawfik developed in vitro compartmentalization (jointly with Andrew D. Griffiths).This technology enables the compartmentalization of single DNA/RNA molecules in emulsion droplets, thus providing cell-like compartment, in which genes can be replicated, transcribed and translated. This technology allowed directed enzyme evolution to be performed without the involvement of living cells, and also became the basis of massive parallel sequencing methods such as 454 sequencing or SOLID, and of digital polymerase chain reaction.
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论文共 309 篇作者统计合作学者相似作者
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Journal of the American Chemical Societyno. 15 (2023): 8344-8354
Fanindra Kumar Deshmukh,Gili Ben-Nissan,Maya A. Olshina,Maria G. Füzesi-Levi, Caley Polkinghorn, Galina Arkind,Yegor Leushkin, Irit Fainer,Sarel J. Fleishman,Dan Tawfik,Michal Sharon
Nature Communicationsno. 1 (2023): 1-24
Orly Dym, Nidhi Aggawal, Yaacov Ashani,Shira Albeck,Tamar Unger,Shelly Hamer Rogotner,Israel Silman,Dan S. Tawfik,Joel L. Sussman
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Manas Seal, Orit Weil‐Ktorza,Dragana Despotović,Dan S. Tawfik,Yaakov Levy,Norman Metanis,Liam M. Longo,Daniella Goldfarb
Journal of the American Chemical Societyno. 45 (2022): 20976-20976
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biorxiv(2022)
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