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My research program is dedicated to the investigation of the structure-function relationships in nucleic acids and protein-nucleic acid complexes that play determinant roles in infectious diseases. The overarching goal is to identify therapeutic targets and to drive drug discovery and diagnostics for HIV, hepatitis C, Zika, and other RNA viruses. To achieve this goal, my group follows a unique cross-disciplinary approach that combines cutting-edge biophysical, biochemical, computational, and omics techniques with novel technologies based on mass spectrometry developed in the lab. Currently funded projects include the investigation of regulatory mechanisms of viral processes involving RNA post-transcriptional modifications (PTMs) and their possible role in mediating the potentiating effects of drugs of abuse on HIV-1 replication.
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论文共 51 篇作者统计合作学者相似作者
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Daniele Fabris, Harold S. Schwenk Sr
MASS SPECTROMETRY REVIEWS (2024)
MASS SPECTROMETRY REVIEWSno. 1 (2024): 5-38
Thomas Kenderdine,William McIntyre,Ghazaleh Yassaghi,Daniele Rollo, Alexander Bunkowski,Lukas Goerlach,Detlev Suckau, Guillaume Tremintin, Michael Greig, Christopher Bell,Daniele Fabris
Journal of the American Society for Mass Spectrometryno. 10 (2023): 2296-2307
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Ion Mobility-Mass SpectrometryNew Developments in Mass Spectrometry (2021): 461-495
William D McIntyre,Reza Nemati,Mehraveh Salehi, Colin C Aldrich, Molly FitzGibbon,Limin Deng,Manuel A Pazos,Rebecca E Rose, Botros Toro,Rachel E Netzband,Cara T Pager, Ingrid P Robinson,
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D-Core
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