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职业迁徙
个人简介
Research Interests
My lab studies the molecular events involved in the battle between host and pathogens, in particular between RNA viruses and humankind. Using various methods ranging from biochemistry, biophysics, structural biology, and cell biology, we successfully answered interesting and demanding questions in the fields of viral replication and host defense systems. Our long-term goal is to better understand the conflict between host and pathogens and improve the well-being of humankind. My lab’s research focuses on the following two interrelated directions: 1) RNA virus transcription, replication, and the generation of pathogenic RNA species; 2) Host defense mechanisms involved in pathogenic RNA sensing and processing. We would like to exercise molecular engineering targeting RNA and RNA-protein complexes to develop new methods and tools for research and therapies.
My lab studies the molecular events involved in the battle between host and pathogens, in particular between RNA viruses and humankind. Using various methods ranging from biochemistry, biophysics, structural biology, and cell biology, we successfully answered interesting and demanding questions in the fields of viral replication and host defense systems. Our long-term goal is to better understand the conflict between host and pathogens and improve the well-being of humankind. My lab’s research focuses on the following two interrelated directions: 1) RNA virus transcription, replication, and the generation of pathogenic RNA species; 2) Host defense mechanisms involved in pathogenic RNA sensing and processing. We would like to exercise molecular engineering targeting RNA and RNA-protein complexes to develop new methods and tools for research and therapies.
研究兴趣
论文共 103 篇作者统计合作学者相似作者
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Bing Liang Alvin Chew, An Qi Ngoh,Wint Wint Phoo, Mei Jie Grace Weng, Ho Jun Sheng,Kitti Wing Ki Chan, Eddie Yong Jun Tan,Terri Gelbart,Chenrui Xu,Gene S. Tan,Subhash G. Vasudevan,Dahai Luo
npj Virusesno. 1 (2024): 1-9
Jessica R. Spengler, Kara Carter,Leen Delang,David Durantel,Brian B. Gowen,Lara J. Herrero,Brett Hurst,Zlatko Janeba, Robert Jordan,Dahai Luo,Chris Meier,Jennifer Moffat,
Antiviral Research (2023): 105678-105678
Advances in immunology (2023): 1-74
The Journal of biological chemistryno. 12 (2023): 105415-105415
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2023): 2137-2146
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