基本信息
浏览量:5
职业迁徙
个人简介
Research Synopsis
Physics of x-ray imaging systems: cone beam, x-ray scatter, innovative imaging geometries
Contrast agents for image-guided therapy
Advanced processes for image-guided procedures
Integration of functional imaging data into the radiation therapy process
Radiation therapy, a proven cancer treatment, is employed to treat fifty percent of all cancer patients. Recent advances in the techniques of radiation delivery have highlighted the advantages of increasing the precision with which the radiotherapeutic dose distribution can be applied within the body. The vast majority of work in Dr. Jaffray’s laboratory focuses on the development of novel imaging systems and concepts to improve the precision of therapy by generating images at the time of therapy for the purpose of guiding the treatment delivery.
Recent developments have included the construction of megavoltage and kilovoltage imaging systems based upon high-performance charged coupled device cameras, prototyping, and evaluation of amorphous-silicon based large-area detectors for megavoltage work. In addition, a kilovoltage cone-beam computed tomography (CT) system has been developed. These systems have been integrated with the megavoltage treatment devices to improve the precision with which the therapy could be executed without the interference of mechanical immobilization systems. The cone-beam CT approach has also been extended to a mobile C-arm for intra-operative imaging and therapy guidance.
A direct by-product of these investigations is the development of clinical processes that can use the images generated by these systems in a sensible and robust fashion. The development of such image-guidance processes is an active area of ongoing research in the program. This area has been broadened through the use of cinematographic magnetic resonance imaging (MR) sequences that permit the spatial instabilities that are inherent in the human body to be assessed. These assessments describe a lower limit on the precision with which non-invasive therapy can be applied and they must be considered in the development of robust treatment regimens.
研究兴趣
论文共 568 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Kang Qin,Kaiwen Wang,Shenduo Li,Lingzhi Hong, Priyadharshini Padmakumar,Rinsurongkawong Waree,Shawna M. Hubert,Xiuning Le,Natalie Vokes,Kunal Rai,Ara Vaporciyan,Don L. Gibbons,
Bozidar Casar,Ignasi Mendez,Eduard Gershkevitsh,Sonja Wegener,David Jaffray, Robert Heaton,Csilla Pesznyak,Gabor Stelczer,Wojciech Bulski,Krzysztof Chelminski, Georgiy Smirnov, Natalia Antipina,
Physics in medicine and biologyno. 3 (2024)
Sheeba J. Sujit,Muhammad Aminu,Tatiana V. Karpinets,Pingjun Chen,Maliazurina B. Saad,Morteza Salehjahromi, John D. Boom, Mohamed Qayati, James M. George, Haley Allen,Mara B. Antonoff,Lingzhi Hong,
Nature Communicationsno. 1 (2024)
Medical Physicsno. S1 (2023): 54-57
Laurence Court,Ajay Aggarwal,Hester Burger,Carlos Cardenas,Christine Chung,Raphael Douglas,Monique du Toit,David Jaffray,Anuja Jhingran, Michael Mejia,Raymond Mumme, Sikudhani Muya,
Chun-Rong Wang,Javed Mahmood,Qin-Rong Zhang,Ali Vedadi, Jenny Warrington,Ning Ou,Robert G. Bristow,David A. Jaffray,Qing-Bin Lu
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn