基本信息
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职业迁徙
个人简介
Research Interest:
Synthetic Organic Chemistry, Using Synthetic Chemistry to Study Biological Problems, Chemical Glycobiology, Development of Chemical Agents for Treatments of Glycosylation-related Diseases, Development of Cancer Vaccine.
Dr. Li's research programmes:
Our research interests include synthetic organic chemistry, chemical biology, drug discovery, synthetic protein chemistry and carbohydrate chemistry.
Synthetic Organic Chemistry
One of obstacles for studying glycosylation is the limited access to glycoconjugates (oligosaccharides, glycolipids, glycoproteins). We are interested in developing novel glycosylation methods, (glyco) peptide/protein ligations, and automated oligosaccharide synthesis to rapidly prepare biologically important glycoconjugates and other bioactive molecules, such as antibiotics, and anticancer
Chemical Biology
Chemical tools have allowed for many biological questions to be answered at a molecular level. One long-term goal of this research program is to design and discover fluorogenic reagents for labeling proteins and carbohydrates and sensors for detecting bio- molecules under physiological conditions.
研究兴趣
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ACS CENTRAL SCIENCEno. 2 (2024): 439-446
Angewandte Chemie (International ed. in English)pp.e202403396-e202403396, (2024)
Science China Chemistrypp.1-37, (2024)
ANALYSIS & SENSINGno. 6 (2023)
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