My research at SCERG is focused on the expansion and directed differentiation of as three dimensional (3D) suspension aggregates. Human induced pluripotent stem cells (hiPSC) may be an ideal source for therapy because they can be derived from the patient to be treated, avoiding immune rejection, and they are also ideal for constructing disease models. However, to realize this enormous potential, it is necessary to develop robust and reproducible bioprocesses for human pluripotent stem cells (hPSCs) expansion and controlled differentiation at large scale. The main aim of my research is the development of a scalable and cost-effective culture platform for expansion of hPSCs and their controlled neural and cardiac differentiation under xeno-free chemically-defined conditions.