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个人简介
Dr. Ritchlin's basic science research efforts are directed towards understanding the mechanisms that underlie pathologic bone resorption and new bone formation in psoriatic arthritis and rheumatoid arthritis. Using a translational approach, investigators in his lab are analyzing the cell surface molecules expressed by osteoclast and dendritic cell precursors with the goal to identify susceptibility and response biomarkers in patients with inflammatory arthritis. The lab is also studying the effect of anti-TNF agents on dendritic cell differentiation in RA and PsA patients. In addition, collaborative studies are underway with the lab of Dr. Eddie Schwarz to understand the mechanisms that are responsible for bone marrow edema as recorded on magnetic resonance imaging scans in inflammatory arthritis. The bulk of this work is performed in animal models but insights gained from these studies are applied to the study of human joint diseases such as psoriatic and rheumatoid arthritis.
研究兴趣
论文共 555 篇作者统计合作学者相似作者
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Dermatologic Clinics (2024)
Dermatologic Clinics (2024)
Philip J. Mease,Iain B. McInnes,Lai-Shan Tam, Raji Rajalingam,Steve Peterson, Fareen Hassan,Soumya D. Chakravarty,Christine Contre, Alison Armstrong,Wolf-Henning Boehncke,Christopher Ritchlin
Rheumatology (Oxford, England)no. 4 (2023): 1417-1425
Catriona N. Grant,Lourdes M. Pérez-Chada,Rebecca H. Haberman, Daniel Webster,Oliver FitzGerald,Christopher T. Ritchlin,Vinod Chandran,Cheryl F. Rosen,Brittany Weber,Michael Garshick,Lihi Eder,Soumya Reddy,
Journal of Psoriasis and Psoriatic Arthritisno. 4 (2023): 179-183
Frontiers in immunology (2023): 1237498-1237498
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