Christopher Kevil (Chris Kevil)
教授
Department of Pathology and Translational Pathobiology
School of Medicine, Louisiana State University Health Shreveport;Department of Molecular and Cellular Physiology, Louisiana State University Health Shreveport;Department of Cellular Biology and Anatomy, Louisiana State University Health Shreveport
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基本信息
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个人简介
Work from our laboratory has published new insights into how the gasotransmitter hydrogen sulfide (H2S) regulates ischemic vascular remodeling and how its metabolites are affected during clinical cardiovascular disease. While the field of H2S biomedical research has grown, many key gaps remain in understanding how sulfide metabolites are formed in the vasculature and their ultimate fate. In brief, our team revealed that H2S bioavailability quickly increases during chronic vascular/tissue ischemia contributing to a compensatory increase in nitric oxide levels. We further found that hydrogen sulfide dependent nitric oxide (NO) enhancement occurs in a dual fashion through its generation by nitric oxide synthases and by stimulation of nitrite reduction back to NO in a xanthine oxidase dependent manner.
研究兴趣
论文共 400 篇作者统计合作学者相似作者
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Zaki Al-Yafeai, Shafaqat Ali, Jimmy Brown, Maamannan Venkataraj,Md. Shenuarin Bhuiyan, Abu Saleh Mosa Faisal, Kenneth Densmore, Nicholas E. Goeders,Steven R. Bailey,Steven A. Conrad, John A. Vanchiere,A. Wayne Orr,
JACC: Advances (2024)
Zaki Al-Yafeai, Shafaqat Ali, Jimmy Brown, Maamannan Venkataraj,Md. Shenuarin Bhuiyan, Abu Saleh Mosa Faisal, Kenneth Densmore, Nicholas E. Goeders, Steven R. Bailey,Steven A. Conrad,John A. Vanchiere,A. Wayne Orr,
JACC: Advancespp.100840, (2024)
Ashton N. Jorgensen,Nabil A. Rashdan, K.N. Shashanka Rao,Luisa F. Delgadillo,Gopi K. Kolluru,David M. Krzywanski, Christopher B. Pattillo,Christopher G. Kevil,Hyung W. Nam
Redox Biology (2024): 103085-103085
Alexandra C. Finney, M. Peyton McKinney, Yuhao Liu,Sonia Salvatore, Nam Hyung,Arif Yurdagul,Francisco J. Schopfer,Chris Kevil,Oren Rom
Arteriosclerosis, Thrombosis, and Vascular Biologyno. Suppl_1 (2023)
Redox biology (2023): 102633-102633
Richa Aishwarya,Chowdhury S Abdullah, Naznin Sultana Remex,Sadia Nitu, Brandon Hartman,Judy King, Mohammad Alfrad Nobel Bhuiyan,Oren Rom, Sumitra Miriyala,Manikandan Panchatcharam, A Wayne Orr,Christopher G Kevil,
Muscles (Basel, Switzerland)no. 1 (2023): 51-74
Shripa Amatya,Dylan Tietje-Mckinney, Schaefer Mueller,Maria G Petrillo,Matthew D Woolard, Sushma Bharrhan,A Wayne Orr,Christopher G Kevil,John A Cidlowski,Diana Cruz-Topete
Arteriosclerosis, Thrombosis, and Vascular Biologyno. Suppl_1 (2023)
Lilly Kamberov,Hemangini Dhaibar, Sonya Patel, Jaylen Pruiett,Xinggui Shen,Wayne W Orr,Steven R. Bailey,Christopher G. Kevil,Robert H. Oakley,John A. Cidlowski,Diana Cruz‐Topete
Circulation Researchno. Suppl_1 (2023)
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