Christian Marc Simon

My research interests are focused on understanding the synaptic and cellular mechanisms involved in motor neuron circuits during development and in neurodegenerative diseases, with emphasis on the two main motor neuron diseases, Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS). In particular, I am interested in deciphering cell autonomous and non-cell autonomous mechanisms involved in the onset and progression of disease as well as during normal development of motor neurons.