基本信息
浏览量:165
职业迁徙
个人简介
Prof. Dr. Frezza’s group seeks to understand the contribution of dysregulated metabolism to aging-associated disorders, in particular focusing on cancer. A part of the lab investigates how the loss of the mitochondrial enzyme and tumour suppressor Fumarate Hydratase causes renal cancer. Our work has multiple implications: (1) it will provide a mechanistic understanding of the role of metabolism and small molecule metabolites in human diseases; (2) it will generate experimental and computation tools to identify metabolic vulnerabilities that we can use as pharmacological targets for cancer therapy; (3) it will apply metabolomics and multi-omics analyses, to mouse and human models to identify metabolic markers of disease initiation for clinical application in early detection and for patient stratification.
研究兴趣
论文共 251 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Janine Tutas, Marianna Tolve, Ebru Oezer Yildiz, Lotte Ickert,Ines Klein, Mahan Hosseini,Filip Liebsch, Frederik Dethloff, Patrick Gavalisco,Heike Endepols,Ming Yang,Theodoros Georgomanolis,
biorxiv(2024)
biorxiv(2024)
Metabolic engineering (2024): 297-298
L Peruzzotti-Jametti,C M Willis, R Hamel,G Krzak,J A Reisz,H A Prag,V Wu, Y Xiang,A M R van den Bosch,A M Nicaise, L Roth,G R Bates,
bioRxiv : the preprint server for biology (2024)
Chrysanthi Moschandrea,Vangelis Kondylis,Ioannis Evangelakos,Marija Herholz,Farina Schneider, Christina Schmidt,Ming Yang, Sandra Ehret,Markus Heine,Michelle Y. Jaeckstein,Karolina Szczepanowska, Robin Schwarzer,
Johan Staaf, Daniel Ehinger,Hans Brunnström,Mats Jönsson,Frida Rosengren, Marija Kotevska,Anna Karlsson,Mattias Aine,Christian Frezza,Maria Planck,Elsa Arbajian
crossref(2024)
Joycelyn Tan,Sam Virtue,Dougall M Norris,Olivia J Conway,Ming Yang,Guillaume Bidault, Christopher Gribben, Fatima Lugtu,Ioannis Kamzolas,James R Krycer,Richard J Mills, Lu Liang,
The EMBO journal (2024)
Li Ren Kong,Komal Gupta, Andy Jialun Wu,David Perera, Roland Ivanyi-Nagy, Syed Moiz Ahmed,Tuan Zea Tan, Shawn Lu-Wen Tan, Alessandra Fuddin, Elayanambi Sundaramoorthy, Grace Shiqing Goh, Regina Tong Xin Wong,
Cell (2024)
Marlous Kamp,Jakub Surmacki, Vincent Zecchini,Karolina Chrabaszcz, Marc S. Mondejar,Tim Young,Christian Frezza,Sarah E. Bohndiek
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXI (2023)
引用0浏览0引用
0
0
Almudena Serrano-Benitez,Sophie E. Wells, Lylah Drummond-Clarke,Lilian C. Russo,John Christopher Thomas, Giovanna A. Leal,Mark Farrow, James Michael Edgerton,Shankar Balasubramanian,Ming Yang,Christian Frezza,Amit Gautam,
EMBO JOURNALno. 18 (2023): e113190-e113190
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn