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个人简介
My research focus is on medicinal chemistry of membrane proteins. We are interested in purinergic receptors and related G protein-coupled orphan receptors including G proteins, as well as ectonucleotidases involved in purinergic signal transduction. A broad spectrum of methods is utilized for our research projects including chemical synthesis of bioactive molecules and labelled compounds (molecular probes), (bio)analytical studies, assay development, structure analysis of drug-protein complexes, in vitro pharmacology, and molecular biology. In vivo studies of our compounds are performed in collaboration with colleagues in biology and medicine. My group runs two platforms, a chemical analytics platform with a focus on quantitative analysis, and a compound library with a unique collection of small synthetic molecules and natural products.
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论文共 793 篇作者统计合作学者相似作者
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Scientific reportsno. 1 (2024): 118-118
Julian Breidenbach,Rabea Voget, Yaoyao Si, Alexandra Hingst,Tobias Claff,Katharina Sylvester, Valentina Wolf, Vesa Krasniqi, Abibe Useini,Norbert Sträter,Yukino Ogura,Atsushi Kawaguchi,
Journal of medicinal chemistry (2024)
Philipp Flury, Julian Breidenbach,Nadine Krueger,Rabea Voget,Laura Schaekel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester,Cheila Rocha, Raphael Ditzinger,
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCEno. 2 (2024): 493-514
Tobias Claff, Andhika B. Mahardhika,Victoria J. Vaaßen,Jonathan G. Schlegel,Christin Vielmuth,Renato H. Weiße,Norbert Sträter,Christa E. Müller
Rabea Voget, Julian Breidenbach,Tobias Claff, Alexandra Hingst, Katharina Sylvester,Christian Steinebach,Lan Phuong Vu,Renato H. Weiße,Ulrike Bartz,Norbert Sträter,Christa E. Müller,Michael Gütschow
Tobias Claff, Andhika B Mahardhika,Victoria J Vaaßen,Jonathan G Schlegel,Christin Vielmuth,Renato H Weiße,Norbert Sträter,Christa E Müller
ACS pharmacology & translational scienceno. 5 (2024): 1415-1425
Philipp Flury,Julian Breidenbach,Nadine Krüger,Rabea Voget,Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert,Katharina Sylvester,Cheila Rocha, Raphael Ditzinger,
ACS pharmacology & translational scienceno. 4 (2024): 1195-1196
Ghazl Al Hamwi,Vigneshwaran Namasivayam, Beatriz Büschbell,Robin Gedschold,Stefan Golz,Christa E. Müller
Communications biologyno. 1 (2024): 52-52
Yuki Yamauchi,Sho Konno, Noriko Omura, Narumi Yoshioka, Alexandra Hingst,Michael Gütschow,Christa E Müller, Akihiro Taguchi,Atsuhiko Taniguchi,Atsushi Kawaguchi,Yoshio Hayashi
Hai-Jun Zhang,Michał Ociepa,Molhm Nassir,Bin Zheng,Sarah A. Lewicki,Veronica Salmaso, Helay Baburi,Jessica Nagel,Salahuddin Mirza,Beatriz Bueschbell,Haneen Al-Hroub, Olga Perzanowska,
Nature Chemistryno. 2 (2024): 249-258
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