基本信息
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个人简介
I use genomic assays to study regulated gene expression, focusing on the C/EBP family of transcription factors (TFs) that bind sequence-specific DNA containing methylated cytosines (5mC) in CG dinucleotides. The C/EBP family of TFs binds in the methylated regions of the genome and I am focusing on understanding how the methylated regions communicate with the unmethylated regions to activate gene expression. In parallel, I am using Agilent microarrays containing thousands of DNA features to explore sequence-specific DNA binding of TFs. I can methylate the arrays and examine the consequences on DNA binding.
Areas of Expertise
1) transcription factors 2) coiled-coil 3) CG methylation 4) DNA binding
研究兴趣
论文共 154 篇作者统计合作学者相似作者
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crossref(2023)
Guanhui Wu,Luying Chen, Kristen Huseman,Desiree Tillo,Sreejana Ray,Ta‐Chau Chang,John S. Schneekloth,Charles Vinson, Dazhi Yang
Cancer Researchno. 7_Supplement (2023): 2756-2756
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Kamyar Yazdani, Srinath Seshadri,Desiree Tillo,Mo Yang, Christopher D. Sibley,Charles Vinson,John S. Schneekloth
bioRxiv : the preprint server for biology (2023)
Michael J. Gerdes, Maxim Myakishev, Nicholas A. Frost,Vikas Rishi, Jaideep Moitra,Asha Acharya, Michelle R. Levy, Sang-won Park,Adam Glick,Stuart H. Yuspa,Charles Vinson
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crossref(2023)
CANCER RESEARCHno. 7 (2023)
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Michael J. Gerdes, Maxim Myakishev, Nicholas A. Frost,Vikas Rishi, Jaideep Moitra,Asha Acharya, Michelle R. Levy, Sang-won Park,Adam Glick,Stuart H. Yuspa,Charles Vinson
crossref(2023)
Science Immunologyno. 72 (2022)
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