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Additionally, I collaborate with Dr. Sandra Reznik on research designed to reduce pre-term birth caused by inflammation. We serendipitously-discovered that a solvent known as N,N-dimethylacetamide (DMA) significantly decreased lipopolysaccharide (LPS) -induced pre-term birth in mice. Originally, we were using DMA as a solvent for another compound that was an inhibitor of the enzyme p38a mitogen-activated protein kinase (MAPK). The injection of DMA alone (control group) dose-dependently decreased pre-term birth and levels of certain inflammatory mediators.
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Advanced Vaccination Technologies for Infectious and Chronic Diseasespp.357-390, (2024)
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Free Radical Biology and Medicine (2023): S89-S89
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