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Charles’ scientific achievements have been to discover mechanisms by which cell-matrix interactions control developmental morphogenesis, survival and proliferation, as well as tissue-specific gene expression, in epithelial tissues. By focusing on breast biology, he revealed the central role of integrin adhesion receptors in mammalian cell behaviour, providing a general framework for understanding epithelial tissue development and function.
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Fuhui Chen,Sevim B. Gurler,David Novo,Cigdem Selli,Denis G. Alferez,Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang,Andrew H. Sims,Neil E. Humphreys,Antony Adamson,Andrew Campbell,
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biorxiv(2020)
Nikki R. Paul,Joanna Thomas,Horacio Maldonado,Katarzyna I. Wolanska,Ewa Koper, Jonathan D. Humphries,Adam Byron, Adams George, Nathan Allen,Ian A. Prior,Charles H. Streuli,Martin J. Humphries,
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